| 产品: | 磷酸化 TCTP (Ser46) 抗体 |
| 货号: | AF2423 |
| 描述: | Rabbit polyclonal antibody to Phospho-TCTP (Ser46) |
| 应用: | WB IHC |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Zebrafish, Bovine, Horse, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 23kDa; 20kD(Calculated). |
| 蛋白号: | P13693 |
| RRID: | AB_2845436 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# AF2423, RRID:AB_2845436.
展开/折叠
FLJ27337; Fortilin; Histamine releasing factor; Histamine-releasing factor; HRF; Immunoglobulin E-dependent; p02; p23; TCTP; TCTP_HUMAN; tpt1; Translationally controlled tumor protein; Translationally-controlled tumor protein; Tumor protein translationally controlled 1; tumor protein, translationally-controlled 1;
抗原和靶标
Found in several healthy and tumoral cells including erythrocytes, hepatocytes, macrophages, platelets, keratinocytes, erythroleukemia cells, gliomas, melanomas, hepatoblastomas, and lymphomas. It cannot be detected in kidney and renal cell carcinoma (RCC). Expressed in placenta and prostate.
- P13693 TCTP_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MIIYRDLISHDEMFSDIYKIREIADGLCLEVEGKMVSRTEGNIDDSLIGGNASAEGPEGEGTESTVITGVDIVMNHHLQETSFTKEAYKKYIKDYMKSIKGKLEEQRPERVKPFMTGAAEQIKHILANFKNYQFFIGENMNPDGMVALLDYREDGVTPYMIFFKDGLEMEKC
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P13693 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S9 | Phosphorylation | Uniprot | |
| S15 | Phosphorylation | Uniprot | |
| Y18 | Phosphorylation | Uniprot | |
| K19 | Acetylation | Uniprot | |
| K19 | Ubiquitination | Uniprot | |
| S37 | Phosphorylation | Uniprot | |
| T39 | Phosphorylation | Uniprot | |
| S46 | Phosphorylation | P53350 (PLK1) | Uniprot |
| S53 | Phosphorylation | Uniprot | |
| S64 | Phosphorylation | P53350 (PLK1) | Uniprot |
| T65 | Phosphorylation | Uniprot | |
| Y88 | Phosphorylation | Uniprot | |
| Y91 | Phosphorylation | Uniprot | |
| K93 | Acetylation | Uniprot | |
| K93 | Ubiquitination | Uniprot | |
| Y95 | Phosphorylation | Uniprot | |
| K97 | Acetylation | Uniprot | |
| K97 | Ubiquitination | Uniprot | |
| S98 | Phosphorylation | Uniprot | |
| K102 | Acetylation | Uniprot | |
| K102 | Sumoylation | Uniprot | |
| K102 | Ubiquitination | Uniprot | |
| K112 | Acetylation | Uniprot | |
| K112 | Sumoylation | Uniprot | |
| K112 | Ubiquitination | Uniprot | |
| T116 | Phosphorylation | Uniprot | |
| K123 | Ubiquitination | Uniprot | |
| K130 | Methylation | Uniprot | |
| K130 | Sumoylation | Uniprot | |
| Y159 | Phosphorylation | Uniprot | |
| K164 | Ubiquitination | Uniprot | |
| K171 | Ubiquitination | Uniprot |
研究背景
Involved in calcium binding and microtubule stabilization.
Cytoplasm.
Found in several healthy and tumoral cells including erythrocytes, hepatocytes, macrophages, platelets, keratinocytes, erythroleukemia cells, gliomas, melanomas, hepatoblastomas, and lymphomas. It cannot be detected in kidney and renal cell carcinoma (RCC). Expressed in placenta and prostate.
Interacts with STEAP3.
Belongs to the TCTP family.
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