| 产品: | 磷酸化 SLC31A1 / CTR1 (Thr114) 抗体 |
| 货号: | AF3773 |
| 描述: | Rabbit polyclonal antibody to Phospho-SLC31A1 / CTR1 (Thr114) |
| 应用: | ELISA(peptide) |
| 反应: | Human, Mouse, Rat |
| 分子量: | 21kD(Calculated). |
| 蛋白号: | O15431 |
| RRID: | AB_2847087 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# AF3773, RRID:AB_2847087.
展开/折叠
Copper transport 1 homolog; Copper transporter 1; COPT1; COPT1_HUMAN; CTR1; hCTR1; High affinity copper uptake protein 1; SLC31A1; solute carrier family 31 (copper tansporters) member 1; Solute carrier family 31 member 1;
抗原和靶标
A synthesized peptide derived from human SLC31A1 / CTR1 around the phosphorylation site of Thr114.
- O15431 COPT1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDHSHHMGMSYMDSNSTMQPSHHHPTTSASHSHGGGDSSMMMMPMTFYFGFKNVELLFSGLVINTAGEMAGAFVAVFLLAMFYEGLKIARESLLRKSQVSIRYNSMPVPGPNGTILMETHKTVGQQMLSFPHLLQTVLHIIQVVISYFLMLIFMTYNGYLCIAVAAGAGTGYFLFSWKKAVVVDITEHCH
翻译修饰 - O15431 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S4 | Phosphorylation | Uniprot | |
| S10 | Phosphorylation | Uniprot | |
| Y11 | Phosphorylation | Uniprot | |
| N15 | N-Glycosylation | Uniprot | |
| T27 | O-Glycosylation | Uniprot | |
| K96 | Ubiquitination | Uniprot | |
| S105 | Phosphorylation | Uniprot | |
| T114 | Phosphorylation | Uniprot |
研究背景
High-affinity, saturable copper transporter involved in dietary copper uptake.
O-Glycosylation at Thr-27 protects from proteolytic cleavage in the N-terminal extracellular domain.
Cell membrane>Multi-pass membrane protein.
Note: Localizes to the apical membrane in intestinal epithelial cells.
Homotrimer.
Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
研究领域
· Human Diseases > Drug resistance: Antineoplastic > Platinum drug resistance.
· Organismal Systems > Digestive system > Mineral absorption.
限制条款
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