AFfirm™ FOXJ1 Mouse Monoclonal Antibody - #BF8040

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产品: FOXJ1 小鼠 单克隆 抗体
货号: BF8040
描述: Mouse monoclonal antibody to FOXJ1
应用: WB
反应: Human
预测: Pig, Bovine, Horse, Sheep, Rabbit, Dog
分子量: 60kDa; 45kD(Calculated).
蛋白号: Q92949

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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MSDS
说明书
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实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Mouse
应用:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
克隆:
Monoclonal [AFfirm8040(AFP21836)]
特异性:
FOXJ1 Antibody detects endogenous levels of total FOXJ1.
偶联:
Unconjugated.
纯化:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

FKHL13; Forkhead box J1; Forkhead box protein J1; Forkhead Homologue 4; Forkhead related protein FKHL13; Forkhead-related protein FKHL13; Fox J1; Foxj1; FOXJ1_HUMAN; Hepatocyte nuclear factor 3 forkhead homolog 4; HFH 4; HFH-4; HFH4; HNF 3/forkhead homolog 4; MGC35202;

抗原和靶标

免疫原:

A synthesized peptide derived from human FOXJ1, corresponding to a region within the internal amino acids.

Uniprot:

Q92949(FOXJ1_HUMAN) >>Visit HPA database.

基因/基因ID:
FOXJ1(2302)
表达:
Q92949 FOXJ1_HUMAN:

Testis, oviduct, lung and brain cortex.

描述:
FOXJ1 May play an important role in cell fate determination during lung development and in spermatogenesis. Note:
序列:
MAESWLRLSGAGPAEEAGPEGGLEEPDALDDSLTSLQWLQEFSILNAKAPALPPGGTDPHGYHQVPGSAAPGSPLAADPACLGQPHTPGKPTSSCTSRSAPPGLQAPPPDDVDYATNPHVKPPYSYATLICMAMQASKATKITLSAIYKWITDNFCYFRHADPTWQNSIRHNLSLNKCFIKVPREKDEPGKGGFWRIDPQYAERLLSGAFKKRRLPPVHIHPAFARQAAQEPSAVPRAGPLTVNTEAQQLLREFEEATGEAGWGAGEGRLGHKRKQPLPKRVAKVPRPPSTLLPTPEEQGELEPLKGNFDWEAIFDAGTLGGELGALEALELSPPLSPASHVDVDLTIHGRHIDCPATWGPSVEQAADSLDFDETFLATSFLQHPWDESGSGCLPPEPLFEAGDATLASDLQDWASVGAFL

翻译修饰 - Q92949 作为底物

Site PTM Type Enzyme
S174 Phosphorylation

研究背景

功能:

Transcription factor specifically required for the formation of motile cilia. Acts by activating transcription of genes that mediate assembly of motile cilia, such as CFAP157. Binds the DNA consensus sequences 5'-HWDTGTTTGTTTA-3' or 5'-KTTTGTTGTTKTW-3' (where H is not G, W is A or T, D is not C, and K is G or T). Activates the transcription of a variety of ciliary proteins in the developing brain and lung.

细胞定位:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Testis, oviduct, lung and brain cortex.

蛋白家族:

Belongs to the FOXJ1 family.

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