AFfirm™ ANO9 Mouse Monoclonal Antibody - #BF8053

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产品: ANO9 小鼠 单克隆 抗体
货号: BF8053
描述: Mouse monoclonal antibody to ANO9
应用: WB IHC
反应: Human
分子量: 90kDa; 90kD(Calculated).
蛋白号: A1A5B4

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 100ul RMB¥ 688 2300 现货

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WB Handbook
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产品描述

来源:
Mouse
应用:
WB 1:1000-1:10000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
克隆:
Monoclonal [AFfirm8053]
特异性:
ANO9 Antibody detects endogenous levels of total ANO9.
偶联:
Unconjugated.
纯化:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Ano9; ANO9_HUMAN; Anoctamin-9; p53-induced gene 5 protein; PIG5; TMEM16J; TP53I5; Transmembrane protein 16J; Tumor protein p53-inducible protein 5;

抗原和靶标

免疫原:

A synthesized peptide derived from human ANO9, corresponding to a region within the internal amino acids.

Uniprot:

A1A5B4(ANO9_HUMAN) >>Visit HPA database.

基因/基因ID:
ANO9(338440)
描述:
May act as a calcium-activated chloride channel.
序列:
MQGEESLRILVEPEGDSFPLMEISTCETEASEQWDYVLVAQRHTQRDPRQARQQQFLEELRRKGFHIKVIRDQKQVFFGIRADNSVFGLYRTLLLEPEGPAPHAELAAPTTIPVTTSLRIRIVNFVVMNNKTSAGETFEDLMKDGVFEARFPLHKGEGRLKKTWARWRHMFREQPVDEIRNYFGEKVALYFVWLGWYTYMLVPAALTGLLVFLSGFSLFEASQISKEICEAHDILMCPLGDHSRRYQRLSETCTFAKLTHLFDNDGTVVFAIFMALWATVFLEIWKRQRARVVLHWDLYVWDEEQEEMALQLINCPDYKLRPYQHSYLRSTVILVLTLLMICLMIGMAHVLVVYRVLASALFSSSAVPFLEEQVTTAVVVTGALVHYVTIIIMTKINRCVALKLCDFEMPRTFSERESRFTIRFFTLQFFTHFSSLIYIAFILGRINGHPGKSTRLAGLWKLEECHASGCMMDLFVQMAIIMGLKQTLSNCVEYLVPWVTHKCRSLRASESGHLPRDPELRDWRRNYLLNPVNTFSLFDEFMEMMIQYGFTTIFVAAFPLAPLLALFSNLVEIRLDAIKMVWLQRRLVPRKAKDIGTWLQVLETIGVLAVIANGMVIAFTSEFIPRVVYKYRYSPCLKEGNSTVDCLKGYVNHSLSVFHTKDFQDPDGIEGSENVTLCRYRDYRNPPDYNFSEQFWFLLAIRLAFVILFEHVALCIKLIAAWFVPDIPQSVKNKVLEVKYQRLREKMWHGRQRLGGVGAGSRPPMPAHPTPASIFSARSTDV

翻译修饰 - A1A5B4 作为底物

Site PTM Type Enzyme
T412 Phosphorylation
S414 Phosphorylation
Y633 Phosphorylation
S634 Phosphorylation

研究背景

功能:

Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide (By similarity). Does not exhibit calcium-activated chloride channel (CaCC) activity. Can inhibit the activity of ANO1.

细胞定位:

Cell membrane>Multi-pass membrane protein.
Note: Shows predominantly an intracellular localization with a weak expression in the cell membrane.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
蛋白家族:

Belongs to the anoctamin family.

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