产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
展开/折叠
ABHD3; Abhydrolase domain containing 3; Abhydrolase domain containing protein 3; Alpha/beta hydrolase domain containing protein 3; LABH3; Lung alpha/beta hydrolase 3; MGC11259;
抗原和靶标
- Q8WU67 ABHD3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MQRLAMDLRMLSRELSLYLEHQVRVGFFGSGVGLSLILGFSVAYAFYYLSSIAKKPQLVTGGESFSRFLQDHCPVVTETYYPTVWCWEGRGQTLLRPFITSKPPVQYRNELIKTADGGQISLDWFDNDNSTCYMDASTRPTILLLPGLTGTSKESYILHMIHLSEELGYRCVVFNNRGVAGENLLTPRTYCCANTEDLETVIHHVHSLYPSAPFLAAGVSMGGMLLLNYLGKIGSKTPLMAAATFSVGWNTFACSESLEKPLNWLLFNYYLTTCLQSSVNKHRHMFVKQVDMDHVMKAKSIREFDKRFTSVMFGYQTIDDYYTDASPSPRLKSVGIPVLCLNSVDDVFSPSHAIPIETAKQNPNVALVLTSYGGHIGFLEGIWPRQSTYMDRVFKQFVQAMVEHGHELS
翻译修饰 - Q8WU67 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K55 | Ubiquitination | Uniprot | |
| K102 | Ubiquitination | Uniprot | |
| Y156 | Phosphorylation | Uniprot | |
| Y169 | Phosphorylation | Uniprot | |
| K288 | Ubiquitination | Uniprot | |
| K297 | Ubiquitination | Uniprot | |
| K299 | Ubiquitination | Uniprot | |
| K332 | Ubiquitination | Uniprot | |
| K395 | Ubiquitination | Uniprot |
研究背景
Phospholipase that may play a role in phospholipids remodeling. May selectively cleave myristate (C14)-containing phosphatidylcholines through its predominant phospholipase 1 activity, cleaving preferentially acyl groups in sn1 position. In parallel, may have a minor phospholipase 2 activity acting on acyl groups in position sn2. In addition to (C14)-containing phosphatidylcholines, may also act on other medium-chain-containing and oxidatively truncated phospholipids.
Membrane>Single-pass type II membrane protein.
Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.
限制条款
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