产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
展开/折叠
CLASP; CLK4 associating serine/arginine rich protein; Clk4 associating SR related protein; FLJ90109; SFRS16; Splicing factor, arginine/serine rich 16 (suppressor of white apricot homolog, Drosophila); Splicing factor, arginine/serine rich 16; Suppressor of white apricot homolog 2; SWAP2;
抗原和靶标
- Q8N2M8 CLASR_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MWHEARKHERKLRGMMVDYKKRAERRREYYEKIKKDPAQFLQVHGRACKVHLDSAVALAAESPVNMMPWQGDTNNMIDRFDVRAHLDHIPDYTPPLLTTISPEQESDERKCNYERYRGLVQNDFAGISEEQCLYQIYIDELYGGLQRPSEDEKKKLAEKKASIGYTYEDSTVAKVEKAAEKPEEEESAAEEESNSDEDEVIPDIDVEVDVDELNQEQVADLNKQATTYGMADGDFVRMLRKDKEEAEAIKHAKALEEEKAMYSGRRSRRQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRSRSPTPGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRSRSRSRSPHYRH
翻译修饰 - Q8N2M8 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| R13 | Methylation | Uniprot | |
| S101 | Phosphorylation | Uniprot | |
| S106 | Phosphorylation | Uniprot | |
| Y228 | Phosphorylation | Uniprot | |
| K259 | Sumoylation | Uniprot | |
| S263 | Phosphorylation | Uniprot | |
| S267 | Phosphorylation | Uniprot | |
| S285 | Phosphorylation | Uniprot | |
| S288 | Phosphorylation | Uniprot | |
| S294 | Phosphorylation | Uniprot | |
| T296 | Phosphorylation | Uniprot | |
| Y297 | Phosphorylation | Uniprot | |
| Y300 | Phosphorylation | Uniprot | |
| S305 | Phosphorylation | Uniprot | |
| S308 | Phosphorylation | Uniprot | |
| S309 | Phosphorylation | Uniprot | |
| S317 | Phosphorylation | Uniprot | |
| T319 | Phosphorylation | Uniprot | |
| T327 | Phosphorylation | Uniprot | |
| T330 | Phosphorylation | Uniprot | |
| S331 | Phosphorylation | Uniprot | |
| S335 | Phosphorylation | Uniprot | |
| S379 | Phosphorylation | Uniprot | |
| S380 | Phosphorylation | Uniprot | |
| S381 | Phosphorylation | Uniprot | |
| S382 | Phosphorylation | Uniprot | |
| T389 | Phosphorylation | Uniprot | |
| S390 | Phosphorylation | Uniprot | |
| S391 | Phosphorylation | Uniprot | |
| S394 | Phosphorylation | Uniprot | |
| S395 | Phosphorylation | Uniprot | |
| S417 | Phosphorylation | Uniprot | |
| S419 | Phosphorylation | Uniprot | |
| S421 | Phosphorylation | Uniprot | |
| S423 | Phosphorylation | Uniprot | |
| Y432 | Phosphorylation | Uniprot | |
| S435 | Phosphorylation | Uniprot | |
| S456 | Phosphorylation | Uniprot | |
| R460 | Methylation | Uniprot | |
| S471 | Phosphorylation | Uniprot | |
| S497 | Phosphorylation | Uniprot | |
| S499 | Phosphorylation | Uniprot | |
| S501 | Phosphorylation | Uniprot | |
| S503 | Phosphorylation | Uniprot | |
| S505 | Phosphorylation | Uniprot | |
| S511 | Phosphorylation | Uniprot | |
| S515 | Phosphorylation | Uniprot | |
| S521 | Phosphorylation | Uniprot | |
| S531 | Phosphorylation | Uniprot | |
| S533 | Phosphorylation | Uniprot | |
| S535 | Phosphorylation | Uniprot | |
| S547 | Phosphorylation | Uniprot | |
| K556 | Acetylation | Uniprot | |
| K556 | Sumoylation | Uniprot | |
| K563 | Acetylation | Uniprot | |
| K571 | Sumoylation | Uniprot | |
| T573 | Phosphorylation | Uniprot | |
| S642 | Phosphorylation | Uniprot | |
| S645 | Phosphorylation | Uniprot | |
| S647 | Phosphorylation | Uniprot | |
| S649 | Phosphorylation | Uniprot | |
| Y652 | Phosphorylation | Uniprot |
研究背景
Probably functions as an alternative splicing regulator. May regulate the mRNA splicing of genes such as CLK1. May act by regulating members of the CLK kinase family (By similarity).
Phosphorylated in vitro by CLK4.
Nucleus.
Probably interacts with CLK4.
Belongs to the splicing factor SR family.
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