产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
展开/折叠
AIFL; Aifm3; AIFM3_HUMAN; Apoptosis inducing factor 3; Apoptosis inducing factor like; Apoptosis inducing factor like protein; Apoptosis inducing factor, mitochondrion associated; Apoptosis-inducing factor 3; Apoptosis-inducing factor-like protein; FLJ30473; FLJ45137;
抗原和靶标
Ubiquitous. Expressed in bone marrow, cerebral cortex, liver, ovary, thymus, thyroid gland and tongue (at protein level).
- Q96NN9 AIFM3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGGCFSKPKPVELKIEVVLPEKERGKEELSASGKGSPRAYQGNGTARHFHTEERLSTPHPYPSPQDCVEAAVCHVKDLENGQMREVELGWGKVLLVKDNGEFHALGHKCPHYGAPLVKGVLSRGRVRCPWHGACFNISTGDLEDFPGLDSLHKFQVKIEKEKVYVRASKQALQLQRRTKVMAKCISPSAGYSSSTNVLIVGAGAAGLVCAETLRQEGFSDRIVLCTLDRHLPYDRPKLSKSLDTQPEQLALRPKEFFRAYGIEVLTEAQVVTVDVRTKKVVFKDGFKLEYSKLLLAPGSSPKTLSCKGKEVENVFTIRTPEDANRVVRLARGRNVVVVGAGFLGMEVAAYLTEKAHSVSVVELEETPFRRFLGERVGRALMKMFENNRVKFYMQTEVSELRGQEGKLKEVVLKSSKVVRADVCVVGIGAVPATGFLRQSGIGLDSRGFIPVNKMMQTNVPGVFAAGDAVTFPLAWRNNRKVNIPHWQMAHAQGRVAAQNMLAQEAEMSTVPYLWTAMFGKSLRYAGYGEGFDDVIIQGDLEELKFVAFYTKGDEVIAVASMNYDPIVSKVAEVLASGRAIRKREVELFVLHSKTGDMSWLTGKGS
翻译修饰 - Q96NN9 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S36 | Phosphorylation | Uniprot | |
| T45 | Phosphorylation | Uniprot | |
| S415 | Phosphorylation | Uniprot | |
| T433 | Phosphorylation | Uniprot | |
| S439 | Phosphorylation | Uniprot | |
| S445 | Phosphorylation | Uniprot | |
| T470 | Phosphorylation | Uniprot | |
| S605 | Phosphorylation | Uniprot |
研究背景
Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential.
Mitochondrion.
Note: Does not translocate to the nucleus upon induction of apoptosis.
Ubiquitous. Expressed in bone marrow, cerebral cortex, liver, ovary, thymus, thyroid gland and tongue (at protein level).
The Rieske domain induces apoptosis.
Belongs to the FAD-dependent oxidoreductase family.
限制条款
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