产品描述
来源:
Mouse
应用:
WB 1:500-1:3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
反应:
Human,Mouse,Rat
克隆:
Monoclonal [AFfirm8531]
偶联:
Unconjugated.
纯化:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:
展开/折叠
HBP; HDL binding protein; HDL-binding protein; HDLBP; high density lipoprotein binding protein; high density lipoprotein binding protein (vigilin); High density lipoprotein-binding protein; PRO2900; VGL; Vigilin; VIGLN_HUMAN;
抗原和靶标
免疫原:
Uniprot:
基因/基因ID:
序列:
- Q00341 VIGLN_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSSVAVLTQESFAEHRSGLVPQQIKVATLNSEEESDPPTYKDAFPPLPEKAACLESAQEPSGAWGNKIRPIKASVITQVFHVPLEERKYKDMNQFGEGEQAKICLEIMQRTGAHLELSLAKDQGLSIMVSGKLDAVMKARKDIVARLQTQASATVAIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDPSNQIKITGTKEGIEKARHEVLLISAEQDKRAVERLEVEKAFHPFIAGPYNRLVGEIMQETGTRINIPPPSVNRTEIVFTGEKEQLAQAVARIKKIYEEKKKKTTTIAVEVKKSQHKYVIGPKGNSLQEILERTGVSVEIPPSDSISETVILRGEPEKLGQALTEVYAKANSFTVSSVAAPSWLHRFIIGKKGQNLAKITQQMPKVHIEFTEGEDKITLEGPTEDVNVAQEQIEGMVKDLINRMDYVEINIDHKFHRHLIGKSGANINRIKDQYKVSVRIPPDSEKSNLIRIEGDPQGVQQAKRELLELASRMENERTKDLIIEQRFHRTIIGQKGERIREIRDKFPEVIINFPDPAQKSDIVQLRGPKNEVEKCTKYMQKMVADLVENSYSISVPIFKQFHKNIIGKGGANIKKIREESNTKIDLPAENSNSETIIITGKRANCEAARSRILSIQKDLANIAEVEVSIPAKLHNSLIGTKGRLIRSIMEECGGVHIHFPVEGSGSDTVVIRGPSSDVEKAKKQLLHLAEEKQTKSFTVDIRAKPEYHKFLIGKGGGKIRKVRDSTGARVIFPAAEDKDQDLITIIGKEDAVREAQKELEALIQNLDNVVEDSMLVDPKHHRHFVIRRGQVLREIAEEYGGVMVSFPRSGTQSDKVTLKGAKDCVEAAKKRIQEIIEDLEAQVTLECAIPQKFHRSVMGPKGSRIQQITRDFSVQIKFPDREENAVHSTEPVVQENGDEAGEGREAKDCDPGSPRRCDIIIISGRKEKCEAAKEALEALVPVTIEVEVPFDLHRYVIGQKGSGIRKMMDEFEVNIHVPAPELQSDIIAITGLAANLDRAKAGLLERVKELQAEQEDRALRSFKLSVTVDPKYHPKIIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAILRIVGELEQMVSEDVPLDHRVHARIIGARGKAIRKIMDEFKVDIRFPQSGAPDPNCVTVTGLPENVEEAIDHILNLEEEYLADVVDSEALQVYMKPPAHEEAKAPSRGFVVRDAPWTASSSEKAPDMSSSEEFPSFGAQVAPKTLPWGPKR
翻译修饰 - Q00341 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S2 | Acetylation | Uniprot | |
| T8 | Phosphorylation | O14757 (CHEK1) | Uniprot |
| S11 | Phosphorylation | Uniprot | |
| K25 | Ubiquitination | Uniprot | |
| T28 | Phosphorylation | Uniprot | |
| S31 | Phosphorylation | Uniprot | |
| S35 | Phosphorylation | Uniprot | |
| T39 | Phosphorylation | Uniprot | |
| Y40 | Phosphorylation | Uniprot | |
| K41 | Ubiquitination | Uniprot | |
| K90 | Ubiquitination | Uniprot | |
| T111 | Phosphorylation | Uniprot | |
| S126 | Phosphorylation | Uniprot | |
| K138 | Ubiquitination | Uniprot | |
| K159 | Ubiquitination | Uniprot | |
| K172 | Ubiquitination | Uniprot | |
| K179 | Ubiquitination | Uniprot | |
| K197 | Ubiquitination | Uniprot | |
| K202 | Ubiquitination | Uniprot | |
| S216 | Phosphorylation | Uniprot | |
| K221 | Ubiquitination | Uniprot | |
| K231 | Ubiquitination | Uniprot | |
| Y241 | Phosphorylation | Uniprot | |
| T271 | Phosphorylation | Uniprot | |
| K274 | Ubiquitination | Uniprot | |
| K294 | Ubiquitination | Uniprot | |
| T296 | Phosphorylation | Uniprot | |
| T297 | Phosphorylation | Uniprot | |
| K308 | Acetylation | Uniprot | |
| K308 | Ubiquitination | Uniprot | |
| K314 | Ubiquitination | Uniprot | |
| S317 | Phosphorylation | Uniprot | |
| K349 | Ubiquitination | Uniprot | |
| Y358 | Phosphorylation | Uniprot | |
| K360 | Ubiquitination | Uniprot | |
| S363 | Phosphorylation | Uniprot | |
| S368 | Phosphorylation | Uniprot | |
| K383 | Ubiquitination | Uniprot | |
| K389 | Ubiquitination | Uniprot | |
| T402 | Phosphorylation | Uniprot | |
| Y437 | Phosphorylation | Uniprot | |
| K453 | Ubiquitination | Uniprot | |
| S454 | Phosphorylation | Uniprot | |
| Y465 | Phosphorylation | Uniprot | |
| K466 | Ubiquitination | Uniprot | |
| S468 | Phosphorylation | Uniprot | |
| K477 | Ubiquitination | Uniprot | |
| K494 | Ubiquitination | Uniprot | |
| K510 | Ubiquitination | Uniprot | |
| K526 | Ubiquitination | Uniprot | |
| K536 | Acetylation | Uniprot | |
| K536 | Ubiquitination | Uniprot | |
| K550 | Ubiquitination | Uniprot | |
| S581 | Phosphorylation | Uniprot | |
| Y582 | Phosphorylation | Uniprot | |
| S583 | Phosphorylation | Uniprot | |
| K594 | Ubiquitination | Uniprot | |
| K599 | Ubiquitination | Uniprot | |
| K605 | Ubiquitination | Uniprot | |
| S611 | Phosphorylation | Uniprot | |
| T613 | Phosphorylation | Uniprot | |
| K614 | Ubiquitination | Uniprot | |
| S624 | Phosphorylation | Uniprot | |
| K632 | Methylation | Uniprot | |
| K632 | Ubiquitination | Uniprot | |
| S645 | Phosphorylation | Uniprot | |
| S659 | Phosphorylation | Uniprot | |
| K663 | Ubiquitination | Uniprot | |
| S667 | Phosphorylation | Uniprot | |
| T671 | Phosphorylation | Uniprot | |
| K672 | Ubiquitination | Uniprot | |
| K711 | Ubiquitination | Uniprot | |
| K713 | Ubiquitination | Uniprot | |
| K714 | Ubiquitination | Uniprot | |
| K723 | Ubiquitination | Uniprot | |
| S727 | Phosphorylation | Uniprot | |
| K749 | Ubiquitination | Uniprot | |
| S756 | Phosphorylation | Uniprot | |
| K769 | Ubiquitination | Uniprot | |
| K779 | Ubiquitination | Uniprot | |
| K810 | Ubiquitination | Uniprot | |
| S840 | Phosphorylation | Uniprot | |
| S844 | Phosphorylation | Uniprot | |
| K846 | Ubiquitination | Uniprot | |
| K883 | Ubiquitination | Uniprot | |
| K892 | Methylation | Uniprot | |
| S894 | Phosphorylation | Uniprot | |
| S904 | Phosphorylation | Uniprot | |
| C940 | S-Nitrosylation | Uniprot | |
| S944 | Phosphorylation | Uniprot | |
| K991 | Ubiquitination | Uniprot | |
| S993 | Phosphorylation | Uniprot | |
| K1031 | Ubiquitination | Uniprot | |
| K1039 | Ubiquitination | Uniprot | |
| R1048 | Methylation | Uniprot | |
| K1054 | Ubiquitination | Uniprot | |
| S1056 | Phosphorylation | Uniprot | |
| T1058 | Phosphorylation | Uniprot | |
| K1062 | Ubiquitination | Uniprot | |
| K1066 | Ubiquitination | Uniprot | |
| T1076 | Phosphorylation | Uniprot | |
| K1108 | Ubiquitination | Uniprot | |
| Y1210 | Phosphorylation | Uniprot | |
| S1223 | Phosphorylation | Uniprot | |
| R1224 | Methylation | Uniprot | |
| S1236 | Phosphorylation | Uniprot | |
| S1237 | Phosphorylation | Uniprot | |
| K1240 | Ubiquitination | Uniprot | |
| S1247 | Phosphorylation | Uniprot | |
| S1252 | Phosphorylation | Uniprot | |
| T1261 | Phosphorylation | Uniprot |
研究背景
功能:
Appears to play a role in cell sterol metabolism. It may function to protect cells from over-accumulation of cholesterol.
细胞定位:
Cytoplasm. Nucleus.
限制条款
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