产品: PPP1R7 小鼠 单克隆 抗体
货号: BF8538
描述: Mouse monoclonal antibody to PPP1R7
应用: WB IHC
反应: Human, Rat
预测: Pig, Bovine, Rabbit
分子量: 48 KD; 42kD(Calculated).
蛋白号: Q15435

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Mouse
应用:
WB 1:500-1:3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Rat
克隆:
Monoclonal [AFfirm8538]
偶联:
Unconjugated.
纯化:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

MGC105784; PP1R7_HUMAN; PPP1R7; protein phosphatase 1 regulatory (inhibitor) subunit 7; Protein phosphatase 1 regulatory subunit 22; Protein phosphatase 1 regulatory subunit 7 alpha2; Protein phosphatase 1 regulatory subunit 7; Protein phosphatase 1 regulatory subunit 7 beta1; Protein phosphatase 1 regulatory subunit 7 beta2; SDS 22; SDS22;

抗原和靶标

免疫原:
Uniprot:
基因/基因ID:
表达:
Q15435 PP1R7_HUMAN:

Widely expressed.

序列:
MAAERGAGQQQSQEMMEVDRRVESEESGDEEGKKHSSGIVADLSEQSLKDGEERGEEDPEEEHELPVDMETINLDRDAEDVDLNHYRIGKIEGFEVLKKVKTLCLRQNLIKCIENLEELQSLRELDLYDNQIKKIENLEALTELEILDISFNLLRNIEGVDKLTRLKKLFLVNNKISKIENLSNLHQLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQNLVNLRELYLSHNGIEVIEGLENNNKLTMLDIASNRIKKIENISHLTELQEFWMNDNLLESWSDLDELKGARSLETVYLERNPLQKDPQYRRKVMLALPSVRQIDATFVRF

翻译修饰 - Q15435 作为底物

Site PTM Type Enzyme
A2 Acetylation
S12 Phosphorylation
S24 Phosphorylation
S27 Phosphorylation
K34 Acetylation
S36 Phosphorylation
S37 Phosphorylation
S44 Phosphorylation
S47 Phosphorylation
K49 Ubiquitination
R54 Methylation
R76 Methylation
K90 Ubiquitination
K98 Ubiquitination
K101 Ubiquitination
K111 Ubiquitination
K133 Ubiquitination
K162 Ubiquitination
K167 Ubiquitination
K168 Ubiquitination
K175 Ubiquitination
K178 Ubiquitination
K217 Ubiquitination
K219 Ubiquitination
K222 Ubiquitination
T243 Phosphorylation
K244 Ubiquitination
T277 Phosphorylation
S322 Phosphorylation
Y327 Phosphorylation
K335 Ubiquitination

研究背景

功能:

Regulatory subunit of protein phosphatase 1.

细胞定位:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Widely expressed.

亚基结构:

Interacts with PPP1CA, PPP1CB and PPP1CC/PPP1G isoform 1.

蛋白家族:

Belongs to the SDS22 family.

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