产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
展开/折叠
Dual specificity phosphatase 9; Dual specificity protein phosphatase 9; DUS9_HUMAN; DUSP9; MAP kinase phosphatase 4; Mitogen activated protein kinase phosphatase 4; Mitogen-activated protein kinase phosphatase 4; MKP 4; MKP-4; MKP4; serine/threonine specific protein phosphatase;
抗原和靶标
- Q99956 DUS9_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEGLGRSCLWLRRELSPPRPRLLLLDCRSRELYESARIGGALSVALPALLLRRLRRGSLSVRALLPGPPLQPPPPAPVLLYDQGGGRRRRGEAEAEAEEWEAESVLGTLLQKLREEGYLAYYLQGGFSRFQAECPHLCETSLAGRAGSSMAPVPGPVPVVGLGSLCLGSDCSDAESEADRDSMSCGLDSEGATPPPVGLRASFPVQILPNLYLGSARDSANLESLAKLGIRYILNVTPNLPNFFEKNGDFHYKQIPISDHWSQNLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLVKRKKSNISPNFNFMGQLLDFERSLRLEERHSQEQGSGGQASAASNPPSFFTTPTSDGAFELAPT
翻译修饰 - Q99956 作为底物
Site | PTM Type | Enzyme | Source |
---|---|---|---|
S16 | Phosphorylation | Uniprot | |
S58 | Phosphorylation | Uniprot | |
T193 | Phosphorylation | Uniprot | |
S219 | Phosphorylation | Uniprot | |
Y232 | Phosphorylation | Uniprot | |
T237 | Phosphorylation | Uniprot | |
S262 | Phosphorylation | Uniprot | |
K324 | Ubiquitination | Uniprot | |
S325 | Phosphorylation | Uniprot | |
S328 | Phosphorylation | Uniprot | |
S351 | Phosphorylation | Uniprot | |
S356 | Phosphorylation | Uniprot | |
S361 | Phosphorylation | Uniprot | |
T372 | Phosphorylation | Uniprot | |
T374 | Phosphorylation | Uniprot | |
S375 | Phosphorylation | Uniprot |
研究背景
Inactivates MAP kinases. Has a specificity for the ERK family.
Cytoplasm.
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
研究领域
· Cellular Processes > Cellular community - eukaryotes > Signaling pathways regulating pluripotency of stem cells. (View pathway)
· Environmental Information Processing > Signal transduction > MAPK signaling pathway. (View pathway)
限制条款
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