产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
展开/折叠
SCML2; SCML2_HUMAN; sex comb on midleg like 2 (Drosophila); Sex comb on midleg like 2; Sex comb on midleg like protein 2; Sex comb on midleg, Drosophila, homolog-like 2; Sex comb on midleg-like protein 2;
抗原和靶标
Highly expressed in placenta, thymus and testis. Detected at lower levels in brain, liver, skeletal muscle, pancreas and ovary.
- Q9UQR0 SCML2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGQTVNEDSMDVKKENQEKTPQSSTSSVQRDDFHWEEYLKETGSISAPSECFRQSQIPPVNDFKVGMKLEARDPRNATSVCIATVIGITGARLRLRLDGSDNRNDFWRLVDSPDIQPVGTCEKEGDLLQPPLGYQMNTSSWPMFLLKTLNGSEMASATLFKKEPPKPPLNNFKVGMKLEAIDKKNPYLICPATIGDVKGDEVHITFDGWSGAFDYWCKYDSRDIFPAGWCRLTGDVLQPPGTSVPIVKNIAKTESSPSEASQHSMQSPQKTTLILPTQQVRRSSRIKPPGPTAVPKRSSSVKNITPRKKGPNSGKKEKPLPVICSTSAASLKSLTRDRGMLYKDVASGPCKIVMSTVCVYVNKHGNFGPHLDPKRIQQLPDHFGPGPVNVVLRRIVQACVDCALETKTVFGYLKPDNRGGEVITASFDGETHSIQLPPVNSASFALRFLENFCHSLQCDNLLSSQPFSSSRGHTHSSAEHDKNQSAKEDVTERQSTKRSPQQTVPYVVPLSPKLPKTKEYASEGEPLFAGGSAIPKEENLSEDSKSSSLNSGNYLNPACRNPMYIHTSVSQDFSRSVPGTTSSPLVGDISPKSSPHEVKFQMQRKSEAPSYIAVPDPSVLKQGFSKDPSTWSVDEVIQFMKHTDPQISGPLADLFRQHEIDGKALFLLKSDVMMKYMGLKLGPALKLCYYIEKLKEGKYS
翻译修饰 - Q9UQR0 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S9 | Phosphorylation | Uniprot | |
| K13 | Sumoylation | Uniprot | |
| K19 | Ubiquitination | Uniprot | |
| T20 | Phosphorylation | Uniprot | |
| K40 | Ubiquitination | Uniprot | |
| K64 | Ubiquitination | Uniprot | |
| K68 | Ubiquitination | Uniprot | |
| K123 | Methylation | Uniprot | |
| K161 | Sumoylation | Uniprot | |
| K162 | Ubiquitination | Uniprot | |
| K177 | Sumoylation | Uniprot | |
| K177 | Ubiquitination | Uniprot | |
| K184 | Sumoylation | Uniprot | |
| K184 | Ubiquitination | Uniprot | |
| K248 | Ubiquitination | Uniprot | |
| K252 | Sumoylation | Uniprot | |
| T253 | Phosphorylation | Uniprot | |
| S255 | Phosphorylation | Uniprot | |
| S256 | Phosphorylation | Uniprot | |
| S258 | Phosphorylation | Uniprot | |
| S261 | Phosphorylation | Uniprot | |
| S264 | Phosphorylation | Uniprot | |
| S267 | Phosphorylation | Uniprot | |
| K296 | Acetylation | Uniprot | |
| S299 | Phosphorylation | Uniprot | |
| S300 | Phosphorylation | Uniprot | |
| K302 | Ubiquitination | Uniprot | |
| T305 | Phosphorylation | P24941 (CDK2) , P06493 (CDK1) | Uniprot |
| K318 | Sumoylation | Uniprot | |
| T326 | Phosphorylation | Uniprot | |
| K332 | Ubiquitination | Uniprot | |
| K343 | Ubiquitination | Uniprot | |
| K374 | Ubiquitination | Uniprot | |
| K407 | Acetylation | Uniprot | |
| K482 | Acetylation | Uniprot | |
| K487 | Sumoylation | Uniprot | |
| S495 | Phosphorylation | Uniprot | |
| T496 | Phosphorylation | Uniprot | |
| S499 | Phosphorylation | Uniprot | |
| T503 | Phosphorylation | Uniprot | |
| Y506 | Phosphorylation | Uniprot | |
| S511 | Phosphorylation | P24941 (CDK2) , P06493 (CDK1) | Uniprot |
| K518 | Ubiquitination | Uniprot | |
| Y520 | Phosphorylation | Uniprot | |
| S522 | Phosphorylation | Uniprot | |
| K536 | Sumoylation | Uniprot | |
| K536 | Ubiquitination | Uniprot | |
| K545 | Sumoylation | Uniprot | |
| K545 | Ubiquitination | Uniprot | |
| T567 | Phosphorylation | Uniprot | |
| S568 | Phosphorylation | Uniprot | |
| S570 | Phosphorylation | Uniprot | |
| S576 | Phosphorylation | Uniprot | |
| T581 | Phosphorylation | Uniprot | |
| S582 | Phosphorylation | Uniprot | |
| S583 | Phosphorylation | Uniprot | |
| S590 | Phosphorylation | P06493 (CDK1) , P24941 (CDK2) | Uniprot |
| S593 | Phosphorylation | Uniprot | |
| S594 | Phosphorylation | Uniprot | |
| K599 | Sumoylation | Uniprot | |
| K599 | Ubiquitination | Uniprot | |
| K605 | Sumoylation | Uniprot | |
| K605 | Ubiquitination | Uniprot | |
| S606 | Phosphorylation | Uniprot | |
| K621 | Ubiquitination | Uniprot | |
| K663 | Ubiquitination | Uniprot | |
| S670 | Phosphorylation | Uniprot | |
| K680 | Sumoylation | Uniprot |
研究背景
Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development (By similarity).
Nucleus.
Highly expressed in placenta, thymus and testis. Detected at lower levels in brain, liver, skeletal muscle, pancreas and ovary.
Belongs to the SCM family.
限制条款
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