产品: SERC1 小鼠 单克隆 抗体
货号: BF8654
描述: Mouse monoclonal antibody to SERC1
应用: WB
反应: Human
预测: Mouse, Rat
分子量: 48kDa; 50kD(Calculated).
蛋白号: Q9NRX5

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Mouse
应用:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
克隆:
Monoclonal [AFfirm8654]
特异性:
SERC1 Mouse Monoclonal Antibody detects endogenous levels of total SERC1.
偶联:
Unconjugated.
纯化:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

1500011D18Rik; AI315070; AIGP 2; KIAA1253; LRRGT00191; mKIAA1253; SERC1_HUMAN; SERINC1; Serine incorporator 1; TDE1L; TDE2; TMS 2; Tms2; Tumor differentially expressed 1 protein like; Tumor differentially expressed protein 1-like; Tumor differentially expressed protein 2; UNQ396/PRO732;

抗原和靶标

免疫原:

A synthesized peptide derived from human SERC1, corresponding to a region within C-terminal amino acids.

Uniprot:
基因/基因ID:
描述:
SERINC1 Enhances the incorporation of serine into phosphatidylserine and sphingolipids. Belongs to the TDE1 family. Interacts with SPTLC1.
序列:
MGSVLGLCSMASWIPCLCGSAPCLLCRCCPSGNNSTVTRLIYALFLLVGVCVACVMLIPGMEEQLNKIPGFCENEKGVVPCNILVGYKAVYRLCFGLAMFYLLLSLLMIKVKSSSDPRAAVHNGFWFFKFAAAIAIIIGAFFIPEGTFTTVWFYVGMAGAFCFILIQLVLLIDFAHSWNESWVEKMEEGNSRCWYAALLSATALNYLLSLVAIVLFFVYYTHPASCSENKAFISVNMLLCVGASVMSILPKIQESQPRSGLLQSSVITVYTMYLTWSAMTNEPETNCNPSLLSIIGYNTTSTVPKEGQSVQWWHAQGIIGLILFLLCVFYSSIRTSNNSQVNKLTLTSDESTLIEDGGARSDGSLEDGDDVHRAVDNERDGVTYSYSFFHFMLFLASLYIMMTLTNWYRYEPSREMKSQWTAVWVKISSSWIGIVLYVWTLVAPLVLTNRDFD

翻译修饰 - Q9NRX5 作为底物

Site PTM Type Enzyme
G2 Myristoylation
S31 Phosphorylation
S35 Phosphorylation
T36 Phosphorylation
T38 Phosphorylation
N298 N-Glycosylation
K343 Ubiquitination
T345 Phosphorylation
T347 Phosphorylation
S348 Phosphorylation
S351 Phosphorylation
T352 Phosphorylation
S361 Phosphorylation
S364 Phosphorylation
Y410 Phosphorylation
S413 Phosphorylation
S418 Phosphorylation
T421 Phosphorylation

研究背景

功能:

Enhances the incorporation of serine into phosphatidylserine and sphingolipids.

细胞定位:

Endoplasmic reticulum membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
亚基结构:

Interacts with SPTLC1.

蛋白家族:

Belongs to the TDE1 family.

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