产品: ZFPL1 小鼠 单克隆 抗体
货号: BF8732
描述: Mouse monoclonal antibody to ZFPL1
应用: WB
反应: Human
预测: Mouse
分子量: 33-40kD; 34kD(Calculated).
蛋白号: O95159

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产品描述

来源:
Mouse
应用:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
克隆:
Monoclonal [AFfirm8732]
特异性:
ZFPL1 Mouse Monoclonal Antibody detects endogenous levels of ZFPL1.
偶联:
Unconjugated.
纯化:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

D11S750; MCG4; MGC 4; ZFPL 1; Zinc finger protein like 1; Zinc finger protein MCG4; zinc-finger protein in MEN1 region;

抗原和靶标

免疫原:

A synthesized peptide derived from human ZFPL1.

Uniprot:
基因/基因ID:
表达:
O95159 ZFPL1_HUMAN:

Expressed strongly in the exocrine pancreas.

序列:
MGLCKCPKRKVTNLFCFEHRVNVCEHCLVANHAKCIVQSYLQWLQDSDYNPNCRLCNIPLASRETTRLVCYDLFHWACLNERAAQLPRNTAPAGYQCPSCNGPIFPPTNLAGPVASALREKLATVNWARAGLGLPLIDEVVSPEPEPLNTSDFSDWSSFNASSTPGPEEVDSASAAPAFYSQAPRPPASPGRPEQHTVIHMGNPEPLTHAPRKVYDTRDDDRTPGLHGDCDDDKYRRRPALGWLARLLRSRAGSRKRPLTLLQRAGLLLLLGLLGFLALLALMSRLGRAAADSDPNLDPLMNPHIRVGPS

研究背景

功能:

Required for cis-Golgi integrity and efficient ER to Golgi transport. Involved in the maintenance of the integrity of the cis-Golgi, possibly via its interaction with GOLGA2/GM130.

翻译修饰:

Phosphorylated.

细胞定位:

Golgi apparatus>cis-Golgi network membrane>Single-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Expressed strongly in the exocrine pancreas.

亚基结构:

Interacts with GOLGA2/GM130.

蛋白家族:

The B box-type and RING-type zinc fingers although degenerate play a central role in function of the protein.

Belongs to the ZFPL1 family.

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