产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
展开/折叠
CAAX prenyl protease 2; FACE 2; FACE2; Farnesylated protein converting enzyme 2; Farnesylated proteins converting enzyme 2; hRCE 1; hRCE1; Prenyl protein peptidase RCE1; Prenyl protein specific endoprotease 2; RCE 1; RCE 1A; RCE 1B; RCE1 homolog prenyl protein peptidase; RCE1A; RCE1B;
抗原和靶标
A synthesized peptide derived from human RCE1.
- Q9Y256 FACE2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAALGGDGLRLLSVSRPERPPESAALGGLGPGLCCWVSVFSCLSLACSYVGSLYVWKSELPRDHPAVIKRRFTSVLVVSSLSPLCVLLWRELTGIQPGTSLLTLMGFRLEGIFPAALLPLLLTMILFLGPLMQLSMDCPCDLADGLKVVLAPRSWARCLTDMRWLRNQVIAPLTEELVFRACMLPMLAPCMGLGPAVFTCPLFFGVAHFHHIIEQLRFRQSSVGNIFLSAAFQFSYTAVFGAYTAFLFIRTGHLIGPVLCHSFCNYMGFPAVCAALEHPQRRPLLAGYALGVGLFLLLLQPLTDPKLYGSLPLCVLLERAGDSEAPLCS
研究背景
Proteolytically removes the C-terminal three residues of farnesylated and geranylated proteins. Seems to be able to process K-Ras, N-Ras, H-Ras, RAP1B and G-gamma-1.
Ubiquitinated. Undergoes 'Lys-48'- and 'Lys-63'-linked ubiquitination. 'Lys-48' ubiquitination induces its degradation. Deubiquitinated by USP17L2/USP17 that cleaves 'Lys-63'-linked ubiquitin chains.
Endoplasmic reticulum membrane>Multi-pass membrane protein.
Ubiquitous.
Belongs to the peptidase U48 family.
研究领域
· Metabolism > Metabolism of terpenoids and polyketides > Terpenoid backbone biosynthesis.
限制条款
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