AFfirm™ COLGALT1 Mouse Monoclonal Antibody - #BF8774

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产品: COLGALT1 小鼠 单克隆 抗体
货号: BF8774
描述: Mouse monoclonal antibody to COLGALT1
应用: WB
反应: Human
预测: Mouse
分子量: 72kD(Calculated).
蛋白号: Q8NBJ5

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 100ul RMB¥ 888 2300 现货

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产品描述

来源:
Mouse
应用:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
克隆:
Monoclonal [AFfirm8774]
特异性:
COLGALT1 Mouse Monoclonal Antibody detects endogenous levels of COLGALT1.
偶联:
Unconjugated.
纯化:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

FLJ22329; Glycosyltransferase 25 domain containing 1; Hydroxylysine galactosyltransferase 1; Procollagen galactosyltransferase 1;

抗原和靶标

免疫原:

A synthesized peptide derived from human COLGALT1.

Uniprot:

Q8NBJ5(GT251_HUMAN) >>Visit HPA database.

基因/基因ID:
COLGALT1(79709)
表达:
Q8NBJ5 GT251_HUMAN:

Ubiquitous with higher levels in placenta, heart, lung and spleen.

序列:
MAAAPRAGRRRGQPLLALLLLLLAPLPPGAPPGADAYFPEERWSPESPLQAPRVLIALLARNAAHALPTTLGALERLRHPRERTALWVATDHNMDNTSTVLREWLVAVKSLYHSVEWRPAEEPRSYPDEEGPKHWSDSRYEHVMKLRQAALKSARDMWADYILFVDADNLILNPDTLSLLIAENKTVVAPMLDSRAAYSNFWCGMTSQGYYKRTPAYIPIRKRDRRGCFAVPMVHSTFLIDLRKAASRNLAFYPPHPDYTWSFDDIIVFAFSCKQAEVQMYVCNKEEYGFLPVPLRAHSTLQDEAESFMHVQLEVMVKHPPAEPSRFISAPTKTPDKMGFDEVFMINLRRRQDRRERMLRALQAQEIECRLVEAVDGKAMNTSQVEALGIQMLPGYRDPYHGRPLTKGELGCFLSHYNIWKEVVDRGLQKSLVFEDDLRFEIFFKRRLMNLMRDVEREGLDWDLIYVGRKRMQVEHPEKAVPRVRNLVEADYSYWTLAYVISLQGARKLLAAEPLSKMLPVDEFLPVMFDKHPVSEYKAHFSLRNLHAFSVEPLLIYPTHYTGDDGYVSDTETSVVWNNEHVKTDWDRAKSQKMREQQALSREAKNSDVLQSPLDSAARDEL

研究背景

功能:

Beta-galactosyltransferase that transfers beta-galactose to hydroxylysine residues of type I collagen. By acting on collagen glycosylation, facilitates the formation of collagen triple helix. Also involved in the biosynthesis of collagen type IV.

翻译修饰:

N-glycosylated.

细胞定位:

Endoplasmic reticulum lumen.
Note: Colocalized with PLOD3 and mannose binding lectin/MBL2.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Ubiquitous with higher levels in placenta, heart, lung and spleen.

蛋白家族:

Belongs to the glycosyltransferase 25 family.

研究领域

· Metabolism > Amino acid metabolism > Lysine degradation.

· Metabolism > Glycan biosynthesis and metabolism > Other types of O-glycan biosynthesis.

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