产品: FAAH2 小鼠 单克隆 抗体
货号: BF8792
描述: Mouse monoclonal antibody to FAAH2
应用: WB
反应: Human
预测: Human
分子量: 60kD; 58kD(Calculated).
蛋白号: Q6GMR7

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 100ul RMB¥ 2300 现货
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产品描述

来源:
Mouse
应用:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
克隆:
Monoclonal [AFfirm8792]
特异性:
FAAH2 Mouse Monoclonal Antibody detects endogenous levels of FAAH2.
偶联:
Unconjugated.
纯化:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

AMDD; amidase domain containing; amidase domain containing protein; Amidase domain-containing protein; Anandamide amidohydrolase 2; FAAH-2; FAAH2; FAAH2_HUMAN; fatty acid amide hydrolase 2; Fatty-acid amide hydrolase 2; FLJ31204; Oleamide hydrolase 2; RP11-479E16; RP11-479E16.1;

抗原和靶标

免疫原:

A synthesized peptide derived from human FAAH2.

Uniprot:
基因/基因ID:
表达:
Q6GMR7 FAAH2_HUMAN:

Highly expressed in the brain, small intestine and testis. Also expressed in the heart, kidney, liver, lung and prostate.

序列:
MAPSFTARIQLFLLRALGFLIGLVGRAALVLGGPKFASKTPRPVTEPLLLLSGMQLAKLIRQRKVKCIDVVQAYINRIKDVNPMINGIVKYRFEEAMKEAHAVDQKLAEKQEDEATLENKWPFLGVPLTVKEAFQLQGMPNSSGLMNRRDAIAKTDATVVALLKGAGAIPLGITNCSELCMWYESSNKIYGRSNNPYDLQHIVGGSSGGEGCTLAAACSVIGVGSDIGGSIRMPAFFNGIFGHKPSPGVVPNKGQFPLAVGAQELFLCTGPMCRYAEDLAPMLKVMAGPGIKRLKLDTKVHLKDLKFYWMEHDGGSFLMSKVDQDLIMTQKKVVVHLETILGASVQHVKLKKMKYSFQLWIAMMSAKGHDGKEPVKFVDLLGDHGKHVSPLWELIKWCLGLSVYTIPSIGLALLEEKLRYSNEKYQKFKAVEESLRKELVDMLGDDGVFLYPSHPTVAPKHHVPLTRPFNFAYTGVFSALGLPVTQCPLGLNAKGLPLGIQVVAGPFNDHLTLAVAQYLEKTFGGWVCPGKF

研究背景

功能:

Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Hydrolyzes monounsaturated substrate anandamide preferentially as compared to polyunsaturated substrates.

细胞定位:

Membrane>Single-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Highly expressed in the brain, small intestine and testis. Also expressed in the heart, kidney, liver, lung and prostate.

亚基结构:

Homodimer.

蛋白家族:

Belongs to the amidase family.

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