产品: ST3GAL4 小鼠 单克隆 抗体
货号: BF8814
描述: Mouse monoclonal antibody to ST3GAL4
应用: WB
反应: Human
预测: Mouse, Rat
分子量: 35-40kD; 38kD(Calculated).
蛋白号: Q11206

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产品描述

来源:
Mouse
应用:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
克隆:
Monoclonal [AFfirm8814]
特异性:
ST3GAL4 Mouse Monoclonal Antibody detects endogenous levels of ST3GAL4.
偶联:
Unconjugated.
纯化:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Alpha 2 3 sialyltransferase IV; Alpha 2 3 ST; Alpha 3 N acetylneuraminyltransferase; Beta galactoside alpha 2 3 sialyltransferase; CGS23; CMP N acetylneuraminate beta galactosamide alpha 2 3 sialyltransferase; FLJ11867; FLJ46764; Gal NAc6S; NANTA3; SAT 3; SAT3; Sialyltransferase 4C (beta galactosidase alpha 2 3 sialytransferase); Sialyltransferase 4C (beta galactoside alpha 2 3 sialytransferase); SIAT4; SIAT4 C; SIAT4C; ST 4; ST3 beta galactoside alpha 2 3 sialyltransferase 4; ST3Gal III; ST3GAL4; ST3GalIV; ST4; STZ;

抗原和靶标

免疫原:

A synthesized peptide derived from human ST3GAL4.

Uniprot:
基因/基因ID:
表达:
Q11206 SIA4C_HUMAN:

Highly expressed in adult placenta, ovary and testes.

序列:
MVSKSRWKLLAMLALVLVVMVWYSISREDRYIELFYFPIPEKKEPCLQGEAESKASKLFGNYSRDQPIFLRLEDYFWVKTPSAYELPYGTKGSEDLLLRVLAITSSSIPKNIQSLRCRRCVVVGNGHRLRNSSLGDAINKYDVVIRLNNAPVAGYEGDVGSKTTMRLFYPESAHFDPKVENNPDTLLVLVAFKAMDFHWIETILSDKKRVRKGFWKQPPLIWDVNPKQIRILNPFFMEIAADKLLSLPMQQPRKIKQKPTTGLLAITLALHLCDLVHIAGFGYPDAYNKKQTIHYYEQITLKSMAGSGHNVSQEALAIKRMLEMGAIKNLTSF

研究背景

功能:

Catalyzes the formation of the NeuAc-alpha-2,3-Gal-beta-1,4-GlcNAc-, and NeuAc-alpha-2,3-Gal-beta-1,3-GlcNAc- sequences found in terminal carbohydrate groups of glycoproteins and glycolipids. It may be involved in the biosynthesis of the sialyl Lewis X determinant.

翻译修饰:

The soluble form derives from the membrane form by proteolytic processing.

细胞定位:

Golgi apparatus>Golgi stack membrane>Single-pass type II membrane protein. Secreted.
Note: Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Highly expressed in adult placenta, ovary and testes.

蛋白家族:

Belongs to the glycosyltransferase 29 family.

研究领域

· Metabolism > Glycan biosynthesis and metabolism > Glycosphingolipid biosynthesis - lacto and neolacto series.

· Metabolism > Global and overview maps > Metabolic pathways.

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