产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
展开/折叠
cytoplasmic; Cytosolic malate dehydrogenase; Diiodophenylpyruvate reductase; Malate dehydrogenase 1, NAD (soluble); Malate dehydrogenase; Malate dehydrogenase cytoplasmic; MDH s; mdh1; MDHA; MDHC_HUMAN; MDHs; MGC:1375; MOR2; Soluble malate dehydrogenase;
抗原和靶标
- P40925 MDHC_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSEPIRVLVTGAAGQIAYSLLYSIGNGSVFGKDQPIILVLLDITPMMGVLDGVLMELQDCALPLLKDVIATDKEDVAFKDLDVAILVGSMPRREGMERKDLLKANVKIFKSQGAALDKYAKKSVKVIVVGNPANTNCLTASKSAPSIPKENFSCLTRLDHNRAKAQIALKLGVTANDVKNVIIWGNHSSTQYPDVNHAKVKLQGKEVGVYEALKDDSWLKGEFVTTVQQRGAAVIKARKLSSAMSAAKAICDHVRDIWFGTPEGEFVSMGVISDGNSYGVPDDLLYSFPVVIKNKTWKFVEGLPINDFSREKMDLTAKELTEEKESAFEFLSSA
翻译修饰 - P40925 作为底物
Site | PTM Type | Enzyme | Source |
---|---|---|---|
S2 | Acetylation | Uniprot | |
Y22 | Phosphorylation | Uniprot | |
T71 | Phosphorylation | Uniprot | |
K73 | Acetylation | Uniprot | |
K73 | Ubiquitination | Uniprot | |
S89 | Phosphorylation | Uniprot | |
K103 | Acetylation | Uniprot | |
K103 | Ubiquitination | Uniprot | |
K107 | Acetylation | Uniprot | |
K107 | Ubiquitination | Uniprot | |
K110 | Methylation | Uniprot | |
K110 | Ubiquitination | Uniprot | |
S111 | Phosphorylation | Uniprot | |
K118 | Acetylation | Uniprot | |
K118 | Ubiquitination | Uniprot | |
Y119 | Phosphorylation | Uniprot | |
K121 | Acetylation | Uniprot | |
K125 | Ubiquitination | Uniprot | |
C137 | S-Nitrosylation | Uniprot | |
K142 | Acetylation | Uniprot | |
K142 | Ubiquitination | Uniprot | |
K149 | Ubiquitination | Uniprot | |
C154 | S-Nitrosylation | Uniprot | |
K164 | Ubiquitination | Uniprot | |
K170 | Ubiquitination | Uniprot | |
T174 | Phosphorylation | Uniprot | |
K179 | Ubiquitination | Uniprot | |
S188 | Phosphorylation | Uniprot | |
S189 | Phosphorylation | Uniprot | |
T190 | Phosphorylation | Uniprot | |
Y192 | Phosphorylation | Uniprot | |
K199 | Ubiquitination | Uniprot | |
K205 | Ubiquitination | Uniprot | |
Y210 | Phosphorylation | Uniprot | |
K214 | Acetylation | Uniprot | |
K214 | Ubiquitination | Uniprot | |
S217 | Phosphorylation | Uniprot | |
K220 | Ubiquitination | Uniprot | |
R230 | Methylation | Uniprot | |
K236 | Ubiquitination | Uniprot | |
K239 | Ubiquitination | Uniprot | |
S241 | Phosphorylation | Uniprot | |
S242 | Phosphorylation | Uniprot | |
S245 | Phosphorylation | Uniprot | |
T296 | Phosphorylation | Uniprot | |
K298 | Acetylation | Uniprot | |
K298 | Ubiquitination | Uniprot | |
S309 | Phosphorylation | Uniprot | |
K312 | Ubiquitination | Uniprot | |
K318 | Ubiquitination | Uniprot | |
T321 | Phosphorylation | Uniprot | |
K324 | Ubiquitination | Uniprot | |
S326 | Phosphorylation | Uniprot | |
S332 | Phosphorylation | Uniprot | |
S333 | Phosphorylation | Uniprot |
研究背景
ISGylated.
Acetylation at Lys-118 dramatically enhances enzymatic activity and promotes adipogenic differentiation.
Cytoplasm.
Homodimer.
Belongs to the LDH/MDH superfamily. MDH type 2 family.
研究领域
· Metabolism > Carbohydrate metabolism > Citrate cycle (TCA cycle).
· Metabolism > Amino acid metabolism > Cysteine and methionine metabolism.
· Metabolism > Carbohydrate metabolism > Pyruvate metabolism.
· Metabolism > Carbohydrate metabolism > Glyoxylate and dicarboxylate metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
· Metabolism > Global and overview maps > Carbon metabolism.
· Organismal Systems > Excretory system > Proximal tubule bicarbonate reclamation.
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