产品: MDH1 小鼠 单克隆 抗体
货号: BF8844
描述: Mouse monoclonal antibody to MDH1
应用: WB
反应: Human
预测: Mouse, Rat, Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
分子量: 36 kDa; 36kD(Calculated).
蛋白号: P40925

浏览相似产品>>

   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

联系销售

产品描述

来源:
Mouse
应用:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
克隆:
Monoclonal [AFfirm8844]
特异性:
MDH1 Mouse Monoclonal Antibody detects endogenous levels of total MDH1.
偶联:
Unconjugated.
纯化:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

cytoplasmic; Cytosolic malate dehydrogenase; Diiodophenylpyruvate reductase; Malate dehydrogenase 1, NAD (soluble); Malate dehydrogenase; Malate dehydrogenase cytoplasmic; MDH s; mdh1; MDHA; MDHC_HUMAN; MDHs; MGC:1375; MOR2; Soluble malate dehydrogenase;

抗原和靶标

免疫原:
Uniprot:
基因/基因ID:
序列:
MSEPIRVLVTGAAGQIAYSLLYSIGNGSVFGKDQPIILVLLDITPMMGVLDGVLMELQDCALPLLKDVIATDKEDVAFKDLDVAILVGSMPRREGMERKDLLKANVKIFKSQGAALDKYAKKSVKVIVVGNPANTNCLTASKSAPSIPKENFSCLTRLDHNRAKAQIALKLGVTANDVKNVIIWGNHSSTQYPDVNHAKVKLQGKEVGVYEALKDDSWLKGEFVTTVQQRGAAVIKARKLSSAMSAAKAICDHVRDIWFGTPEGEFVSMGVISDGNSYGVPDDLLYSFPVVIKNKTWKFVEGLPINDFSREKMDLTAKELTEEKESAFEFLSSA

翻译修饰 - P40925 作为底物

Site PTM Type Enzyme
S2 Acetylation
Y22 Phosphorylation
T71 Phosphorylation
K73 Acetylation
K73 Ubiquitination
S89 Phosphorylation
K103 Acetylation
K103 Ubiquitination
K107 Acetylation
K107 Ubiquitination
K110 Methylation
K110 Ubiquitination
S111 Phosphorylation
K118 Acetylation
K118 Ubiquitination
Y119 Phosphorylation
K121 Acetylation
K125 Ubiquitination
C137 S-Nitrosylation
K142 Acetylation
K142 Ubiquitination
K149 Ubiquitination
C154 S-Nitrosylation
K164 Ubiquitination
K170 Ubiquitination
T174 Phosphorylation
K179 Ubiquitination
S188 Phosphorylation
S189 Phosphorylation
T190 Phosphorylation
Y192 Phosphorylation
K199 Ubiquitination
K205 Ubiquitination
Y210 Phosphorylation
K214 Acetylation
K214 Ubiquitination
S217 Phosphorylation
K220 Ubiquitination
R230 Methylation
K236 Ubiquitination
K239 Ubiquitination
S241 Phosphorylation
S242 Phosphorylation
S245 Phosphorylation
T296 Phosphorylation
K298 Acetylation
K298 Ubiquitination
S309 Phosphorylation
K312 Ubiquitination
K318 Ubiquitination
T321 Phosphorylation
K324 Ubiquitination
S326 Phosphorylation
S332 Phosphorylation
S333 Phosphorylation

研究背景

翻译修饰:

ISGylated.

Acetylation at Lys-118 dramatically enhances enzymatic activity and promotes adipogenic differentiation.

细胞定位:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
亚基结构:

Homodimer.

蛋白家族:

Belongs to the LDH/MDH superfamily. MDH type 2 family.

研究领域

· Metabolism > Carbohydrate metabolism > Citrate cycle (TCA cycle).

· Metabolism > Amino acid metabolism > Cysteine and methionine metabolism.

· Metabolism > Carbohydrate metabolism > Pyruvate metabolism.

· Metabolism > Carbohydrate metabolism > Glyoxylate and dicarboxylate metabolism.

· Metabolism > Global and overview maps > Metabolic pathways.

· Metabolism > Global and overview maps > Carbon metabolism.

· Organismal Systems > Excretory system > Proximal tubule bicarbonate reclamation.

限制条款

产品的规格、报价、验证数据请以官网为准,官网链接:www.affbiotech.com | www.affbiotech.cn(简体中文)| www.affbiotech.jp(日本語)

产品的数据信息为Affinity所有,未经授权不得收集Affinity官网数据或资料用于商业用途,对抄袭产品数据的行为我们将保留诉诸法律的权利。

产品相关数据会因产品批次、产品检测情况随时调整,如您已订购该产品,请以订购时随货说明书为准,否则请以官网内容为准,官网内容有改动时恕不另行通知。

Affinity保证所销售产品均经过严格质量检测。如您购买的商品在规定时间内出现问题需要售后时,请您在Affinity官方渠道提交售后申请。

产品仅供科学研究使用。不用于诊断和治疗。 

产品未经授权不得转售。

Affinity Biosciences将不会对在使用我们的产品时可能发生的专利侵权或其他侵权行为负责。Affinity Biosciences, Affinity Biosciences标志和所有其他商标所有权归Affinity Biosciences LTD.