产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
展开/折叠
ArfGAP with dual PH domains 1; CENTA 1; CENTA1; Centaurin alpha; GCS1L; p42IP4; Putative MAPK activating protein PM25;
抗原和靶标
A synthesized peptide derived from Human Centaurin alpha 1.
Expressed at highest levels in brain and at lower levels in peripheral blood leukocytes.
- O75689 ADAP1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAKERRRAVLELLQRPGNARCADCGAPDPDWASYTLGVFICLSCSGIHRNIPQVSKVKSVRLDAWEEAQVEFMASHGNDAARARFESKVPSFYYRPTPSDCQLLREQWIRAKYERQEFIYPEKQEPYSAGYREGFLWKRGRDNGQFLSRKFVLTEREGALKYFNRNDAKEPKAVMKIEHLNATFQPAKIGHPHGLQVTYLKDNSTRNIFIYHEDGKEIVDWFNALRAARFHYLQVAFPGAGDADLVPKLSRNYLKEGYMEKTGPKQTEGFRKRWFTMDDRRLMYFKDPLDAFARGEVFIGSKESGYTVLHGFPPSTQGHHWPHGITIVTPDRKFLFACETESDQREWVAAFQKAVDRPMLPQEYAVEAHFKHKP
研究背景
GTPase-activating protein for the ADP ribosylation factor family (Probable). Binds phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4).
Phosphorylated by PRKCA, PRKCI, PRKCZ and PRKD1 in vitro.
Nucleus. Cytoplasm.
Note: Recruited to the plasma membrane upon epidermal growth factor-dependent activation of phosphatidylinositol 4,5-diphosphate (PtdInsP2) 3-kinase.
Expressed at highest levels in brain and at lower levels in peripheral blood leukocytes.
Interacts with PRKCA, PRKCI and PRKCZ. Interacts with the N-terminal region of PRKD1.
限制条款
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