产品: PRLHR 小鼠 单克隆 抗体
货号: BF8973
描述: Mouse monoclonal antibody to PRLHR
应用: WB
反应: Human
预测: Mouse, Rat, Pig, Bovine, Horse, Sheep, Dog
分子量: 41 kDa; 41kD(Calculated).
蛋白号: P49683

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Mouse
应用:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
克隆:
Monoclonal [AFfirm8973]
特异性:
PRLHR Mouse Monoclonal Antibody detects endogenous levels of total PRLHR.
偶联:
Unconjugated.
纯化:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

G protein coupled receptor 10; G-protein coupled receptor 10; GPR 10; GPR10; GR 3; GR3; hGR 3; hGR3; MGC126539; MGC126541; OTTHUMP00000020584; PRLH RECEPTOR; PRLHR; PRLHR_HUMAN; Prolactin releasing hormone receptor; Prolactin releasing peptide receptor; Prolactin-releasing peptide receptor; PrRP receptor; PrRPR; uhr-1;

抗原和靶标

免疫原:
Uniprot:
基因/基因ID:
表达:
P49683 PRLHR_HUMAN:

Only detected in the pituitary gland and in all cell types of pituitary adenomas.

描述:
Receptor for prolactin-releasing peptide (PrRP). Implicated in lactation, regulation of food intake and pain-signal processing.
序列:
MASSTTRGPRVSDLFSGLPPAVTTPANQSAEASAGNGSVAGADAPAVTPFQSLQLVHQLKGLIVLLYSVVVVVGLVGNCLLVLVIARVRRLHNVTNFLIGNLALSDVLMCTACVPLTLAYAFEPRGWVFGGGLCHLVFFLQPVTVYVSVFTLTTIAVDRYVVLVHPLRRRISLRLSAYAVLAIWALSAVLALPAAVHTYHVELKPHDVRLCEEFWGSQERQRQLYAWGLLLVTYLLPLLVILLSYVRVSVKLRNRVVPGCVTQSQADWDRARRRRTFCLLVVIVVVFAVCWLPLHVFNLLRDLDPHAIDPYAFGLVQLLCHWLAMSSACYNPFIYAWLHDSFREELRKLLVAWPRKIAPHGQNMTVSVVI

翻译修饰 - P49683 作为底物

Site PTM Type Enzyme
S244 Phosphorylation

研究背景

功能:

Receptor for prolactin-releasing peptide (PrRP). Implicated in lactation, regulation of food intake and pain-signal processing.

细胞定位:

Cell membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Only detected in the pituitary gland and in all cell types of pituitary adenomas.

亚基结构:

Interacts through its C-terminal region with the PDZ domain-containing proteins GRIP1, GRIP2 and PICK1. Interacts with PDZ domains 4 and 5 of GRIP1 and with the PDZ domain of PICK1.

蛋白家族:

Belongs to the G-protein coupled receptor 1 family.

研究领域

· Environmental Information Processing > Signaling molecules and interaction > Neuroactive ligand-receptor interaction.

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