AFfirm™ MZF-1 Mouse Monoclonal Antibody - #BF9307

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产品: MZF-1 小鼠 单克隆 抗体
货号: BF9307
描述: Mouse monoclonal antibody to MZF-1
应用: WB
反应: Human
预测: Mouse, Rat, Pig, Horse, Dog
分子量: 82 KD; 82kD(Calculated).
蛋白号: P28698

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 100ul RMB¥ 1150 2300 现货

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实验方案
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产品描述

来源:
Mouse
应用:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
克隆:
Monoclonal [AFfirm9307]
特异性:
MZF-1 Mouse Monoclonal Antibody detects endogenous levels of total MZF-1.
偶联:
Unconjugated.
纯化:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Myeloid zinc finger 1; MZF 1; MZF-1; MZF1; MZF1_HUMAN; MZF1B; Zfp98; Zinc finger and SCAN domain containing protein 6; Zinc finger and SCAN domain-containing protein 6; Zinc finger protein 42; ZNF42; ZSCAN6;

抗原和靶标

免疫原:
Uniprot:

P28698(MZF1_HUMAN) >>Visit HPA database.

基因/基因ID:
MZF1(7593)
表达:
P28698 MZF1_HUMAN:

Preferentially expressed in differentiating myeloid cells. Detected in osteoblasts.

序列:
MRPAVLGSPDRAPPEDEGPVMVKLEDSEEEGEAALWDPGPEAARLRFRCFRYEEATGPQEALAQLRELCRQWLRPEVRSKEQMLELLVLEQFLGALPPEIQARVQGQRPGSPEEAAALVDGLRREPGGPRRWVTVQVQGQEVLSEKMEPSSFQPLPETEPPTPEPGPKTPPRTMQESPLGLQVKEESEVTEDSDFLESGPLAATQESVPTLLPEEAQRCGTVLDQIFPHSKTGPEGPSWREHPRALWHEEAGGIFSPGFALQLGSISAGPGSVSPHLHVPWDLGMAGLSGQIQSPSREGGFAHALLLPSDLRSEQDPTDEDPCRGVGPALITTRWRSPRGRSRGRPSTGGGVVRGGRCDVCGKVFSQRSNLLRHQKIHTGERPFVCSECGRSFSRSSHLLRHQLTHTEERPFVCGDCGQGFVRSARLEEHRRVHTGEQPFRCAECGQSFRQRSNLLQHQRIHGDPPGPGAKPPAPPGAPEPPGPFPCSECRESFARRAVLLEHQAVHTGDKSFGCVECGERFGRRSVLLQHRRVHSGERPFACAECGQSFRQRSNLTQHRRIHTGERPFACAECGKAFRQRPTLTQHLRVHTGEKPFACPECGQRFSQRLKLTRHQRTHTGEKPYHCGECGLGFTQVSRLTEHQRIHTGERPFACPECGQSFRQHANLTQHRRIHTGERPYACPECGKAFRQRPTLTQHLRTHRREKPFACQDCGRRFHQSTKLIQHQRVHSAE

翻译修饰 - P28698 作为底物

Site PTM Type Enzyme
S8 Phosphorylation
S27 Phosphorylation
S111 Phosphorylation
T134 Phosphorylation
T169 Phosphorylation
S177 Phosphorylation
S256 Phosphorylation Q16539 (MAPK14) , P27361 (MAPK3)
S274 Phosphorylation Q16539 (MAPK14) , P27361 (MAPK3)
S294 Phosphorylation Q16539 (MAPK14) , P27361 (MAPK3)
S347 Phosphorylation
T592 Phosphorylation
K595 Sumoylation
T618 Phosphorylation
T620 Phosphorylation
K723 Sumoylation

研究背景

功能:

Binds to target promoter DNA and functions as transcription regulator. Regulates transcription from the PADI1 and CDH2 promoter. May be one regulator of transcriptional events during hemopoietic development.

细胞定位:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Preferentially expressed in differentiating myeloid cells. Detected in osteoblasts.

亚基结构:

Homodimer.

蛋白家族:

Belongs to the krueppel C2H2-type zinc-finger protein family.

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