AFfirm™ APPBP2 Mouse Monoclonal Antibody - #BF9346

产品: APPBP2 小鼠 单克隆 抗体
货号: BF9346
描述: Mouse monoclonal antibody to APPBP2
应用: WB
反应: Human
预测: Mouse, Rat, Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
分子量: 67 KD; 67kD(Calculated).
蛋白号: Q92624

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Mouse
应用:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
克隆:
Monoclonal [AFfirm9346]
特异性:
APPBP2 Mouse Monoclonal Antibody detects endogenous levels of total APPBP2.
偶联:
Unconjugated.
纯化:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

amyloid beta precursor protein (cytoplasmic tail) binding protein 2; Amyloid beta precursor protein-binding protein 2; Amyloid protein binding protein 2; Amyloid protein-binding protein 2; APBP2_HUMAN; APP BP2; APP-BP2; Appbp2; PAT1; Protein interacting with APP tail 1;

抗原和靶标

免疫原:
Uniprot:

Q92624(APBP2_HUMAN) >>Visit HPA database.

基因/基因ID:
APPBP2(10513)
序列:
MAAVELEWIPETLYNTAISAVVDNYIRSRRDIRSLPENIQFDVYYKLYQQGRLCQLGSEFCELEVFAKVLRALDKRHLLHHCFQALMDHGVKVASVLAYSFSRRCSYIAESDAAVKEKAIQVGFVLGGFLSDAGWYSDAEKVFLSCLQLCTLHDEMLHWFRAVECCVRLLHVRNGNCKYHLGEETFKLAQTYMDKLSKHGQQANKAALYGELCALLFAKSHYDEAYKWCIEAMKEITAGLPVKVVVDVLRQASKACVVKREFKKAEQLIKHAVYLARDHFGSKHPKYSDTLLDYGFYLLNVDNICQSVAIYQAALDIRQSVFGGKNIHVATAHEDLAYSSYVHQYSSGKFDNALFHAERAIGIITHILPEDHLLLASSKRVKALILEEIAIDCHNKETEQRLLQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSIGNYEKVFEYHNVLSNWNRLRDRQYSVTDALEDVSTSPQSTEEVVQSFLISQNVEGPSC

翻译修饰 - Q92624 作为底物

Site PTM Type Enzyme
K68 Methylation
K68 Ubiquitination
S106 Phosphorylation
K178 Ubiquitination
K187 Ubiquitination
K195 Ubiquitination
K198 Ubiquitination
T237 Phosphorylation
K254 Ubiquitination
K264 Ubiquitination
K283 Ubiquitination
K349 Ubiquitination
K379 Ubiquitination
K396 Ubiquitination
K418 Ubiquitination
K419 Ubiquitination
K430 Ubiquitination
K446 Ubiquitination
K454 Ubiquitination
K504 Ubiquitination
Y517 Phosphorylation
K522 Ubiquitination

研究背景

功能:

May play a role in intracellular protein transport. May be involved in the translocation of APP along microtubules toward the cell surface.

翻译修饰:

Rapidly degraded by the proteasome upon overexpression of a C-terminal fragment of APP.

细胞定位:

Nucleus. Cytoplasm>Cytoskeleton. Membrane>Peripheral membrane protein.
Note: Associated with membranes and microtubules.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
亚基结构:

Binds APP.

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