产品: RPL17 小鼠 单克隆 抗体
货号: BF9347
描述: Mouse monoclonal antibody to RPL17
应用: WB
反应: Human
预测: Mouse, Rat, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus
分子量: 24 KD; 21kD(Calculated).
蛋白号: P18621

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Mouse
应用:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
克隆:
Monoclonal [AFfirm9347]
特异性:
RPL17 Mouse Monoclonal Antibody detects endogenous levels of total RPL17.
偶联:
Unconjugated.
纯化:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

60S ribosomal protein L17; 60S ribosomal protein L23; FLJ92089; Gene encoding putative NFkB activating protein; L17; MGC117162; PD 1; PD-1; PD1; Ribosomal protein L17; RL17_HUMAN; RPL17; rpL23;

抗原和靶标

免疫原:

A synthesized peptide derived from human RPL17, corresponding to a region within C-terminal amino acids.

Uniprot:
基因/基因ID:
表达:
P18621 RL17_HUMAN:

Expressed in pancreas, lung, colon, cystic duct, gall bladder, kidney and liver. Expressed at high levels in the well differentiated pancreatic tumor cell lines HPAF, COLO 357 and Capan-1, the moderately differentiated pancreatic tumor cell lines T3M-4, AsPc-1 and BxPc-3, the poorly differentiated pancreatic tumor cell line MIA PaCa-2, and the pancreatic tumor cell lines of undefined differentiation status such as SW979. Expressed at lower levels in the poorly differentiated pancreatic tumor cell lines HCG-25 and PANC-1.

序列:
MVRYSLDPENPTKSCKSRGSNLRVHFKNTRETAQAIKGMHIRKATKYLKDVTLQKQCVPFRRYNGGVGRCAQAKQWGWTQGRWPKKSAEFLLHMLKNAESNAELKGLDVDSLVIEHIQVNKAPKMRRRTYRAHGRINPYMSSPCHIEMILTEKEQIVPKPEEEVAQKKKISQKKLKKQKLMARE

翻译修饰 - P18621 作为底物

Site PTM Type Enzyme
S5 Phosphorylation
K13 Ubiquitination
S14 Phosphorylation
C15 S-Nitrosylation
K27 Ubiquitination
K37 Acetylation
K37 Methylation
K37 Sumoylation
K37 Ubiquitination
K49 Acetylation
K49 Ubiquitination
K55 Acetylation
K55 Ubiquitination
R69 Methylation
K74 Acetylation
K74 Ubiquitination
K85 Acetylation
K86 Sumoylation
K86 Ubiquitination
S87 Phosphorylation
K96 Ubiquitination
K105 Ubiquitination
K121 Ubiquitination
T129 Phosphorylation
S141 Phosphorylation
S142 Phosphorylation
K159 Sumoylation
K159 Ubiquitination
K167 Ubiquitination
S171 Phosphorylation

研究背景

功能:

Component of the large ribosomal subunit.

组织特异性:

Expressed in pancreas, lung, colon, cystic duct, gall bladder, kidney and liver. Expressed at high levels in the well differentiated pancreatic tumor cell lines HPAF, COLO 357 and Capan-1, the moderately differentiated pancreatic tumor cell lines T3M-4, AsPc-1 and BxPc-3, the poorly differentiated pancreatic tumor cell line MIA PaCa-2, and the pancreatic tumor cell lines of undefined differentiation status such as SW979. Expressed at lower levels in the poorly differentiated pancreatic tumor cell lines HCG-25 and PANC-1.

亚基结构:

Component of the large ribosomal subunit.

蛋白家族:

Belongs to the universal ribosomal protein uL22 family.

研究领域

· Genetic Information Processing > Translation > Ribosome.

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