AFfirm™ VWA5A Mouse Monoclonal Antibody - #BF9351
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
展开/折叠
BCSC 1;BCSC-1;BCSC1;Breast cancer suppressor candidate 1;LHR2A;LOH11CR2A;Loss of heterozygosity 11 chromosomal region 2 gene A;Loss of heterozygosity 11 chromosomal region 2 gene A protein;Ortholog of mouse AW551984;VMA5A_HUMAN;von Willebrand factor A domain containing 5A;von Willebrand factor A domain-containing protein 5A;Vwa5a;
抗原和靶标
Expressed at low level in many tissues. Not expressed in 80% of tumor cell lines tested.
- O00534 VMA5A_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MVHFCGLLTLHREPVPLKSISVSVNIYEFVAGVSATLNYENEEKVPLEAFFVFPMDEDSAVYSFEALVDGKKIVAELQDKMKARTNYEKAISQGHQAFLLEGDSSSRDVFSCNVGNLQPGSKAAVTLKYVQELPLEADGALRFVLPAVLNPRYQFSGSSKDSCLNVKTPIVPVEDLPYTLSMVATIDSQHGIEKVQSNCPLSPTEYLGEDKTSAQVSLAAGHKFDRDVELLIYYNEVHTPSVVLEMGMPNMKPGHLMGDPSAMVSFYPNIPEDQPSNTCGEFIFLMDRSGSMQSPMSSQDTSQLRIQAAKETLILLLKSLPIGCYFNIYGFGSSYEACFPESVKYTQQTMEEALGRVKLMQADLGGTEILAPLQNIYRGPSIPGHPLQLFVFTDGEVTDTFSVIKEVRINRQKHRCFSFGIGEGTSTSLIKGIARASGGTSEFITGKDRMQSKALRTLKRSLQPVVEDVSLSWHLPPGLSAKMLSPEQTVIFRGQRLISYAQLTGRMPAAETTGEVCLKYTLQGKTFEDKVTFPLQPKPDVNLTIHRLAAKSLLQTKDMGLRETPASDKKDALNLSLESGVISSFTAFIAINKELNKPVQGPLAHRDVPRPILLGASAPLKIKCQSGFRKALHSDRPPSASQPRGELMCYKAKTFQMDDYSLCGLISHKDQHSPGFGENHLVQLIYHQNANGSWDLNEDLAKILGMSLEEIMAAQPAELVDSSGWATILAVIWLHSNGKDLKCEWELLERKAVAWMRAHAGSTMPSVVKAAITFLKSSVDPAIFAF
翻译修饰 - O00534 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T9 | Phosphorylation | Uniprot | |
| K72 | Ubiquitination | Uniprot | |
| K80 | Ubiquitination | Uniprot | |
| K89 | Ubiquitination | Uniprot | |
| S92 | Phosphorylation | Uniprot | |
| S104 | Phosphorylation | Uniprot | |
| S106 | Phosphorylation | Uniprot | |
| K122 | Ubiquitination | Uniprot | |
| K128 | Ubiquitination | Uniprot | |
| K160 | Ubiquitination | Uniprot | |
| S162 | Phosphorylation | Uniprot | |
| S202 | Phosphorylation | Uniprot | |
| T204 | Phosphorylation | Uniprot | |
| S289 | Phosphorylation | Uniprot | |
| S291 | Phosphorylation | Uniprot | |
| K310 | Ubiquitination | Uniprot | |
| K358 | Ubiquitination | Uniprot | |
| S381 | Phosphorylation | Uniprot | |
| K447 | Ubiquitination | Uniprot | |
| S485 | Phosphorylation | Uniprot | |
| T489 | Phosphorylation | Uniprot | |
| K525 | Ubiquitination | Uniprot | |
| K597 | Ubiquitination | Uniprot | |
| S617 | Phosphorylation | Uniprot | |
| K621 | Ubiquitination | Uniprot | |
| K623 | Ubiquitination | Uniprot | |
| K630 | Ubiquitination | Uniprot | |
| S634 | Phosphorylation | Uniprot | |
| S639 | Phosphorylation | Uniprot | |
| K653 | Ubiquitination | Uniprot | |
| T654 | Phosphorylation | Uniprot | |
| Y660 | Phosphorylation | Uniprot | |
| S661 | Phosphorylation | Uniprot | |
| S673 | Phosphorylation | Uniprot |
研究背景
May play a role in tumorigenesis as a tumor suppressor. Altered expression of this protein and disruption of the molecular pathway it is involved in, may contribute directly to or modify tumorigenesis.
Expressed at low level in many tissues. Not expressed in 80% of tumor cell lines tested.
限制条款
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