AFfirm™ CXCR1 Mouse Monoclonal Antibody - #BF9374

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产品: CXCR1 小鼠 单克隆 抗体
货号: BF9374
描述: Mouse monoclonal antibody to CXCR1
应用: WB
反应: Human
预测: Human
分子量: 40 kDa; 40kD(Calculated).
蛋白号: P25024

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   规格 价格 库存
 100ul RMB¥ 1150 2300 现货

货期: 当天发货

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MS Report
HPLC Report
MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Mouse
应用:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
克隆:
Monoclonal [AFfirm9374]
特异性:
CXCR1 Mouse Monoclonal Antibody detects endogenous levels of total CXCR1.
偶联:
Unconjugated.
纯化:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

C C; C C CKR 1; C-X-C chemokine receptor type 1; CCCKR1; CD 181; CD128; CD181; CD181 antigen; CDw128a; Chemokine (C X C motif) receptor 1; Chemokine (C X C) receptor 1; Chemokine receptor 1; CKR 1; CMKAR1; CXC-R1; CXCR 1; CXCR-1; CXCR1; CXCR1_HUMAN; High affinity interleukin 8 receptor A; High affinity interleukin-8 receptor A; IL 8 receptor type 1; IL 8R A; IL-8 receptor type 1; IL-8R A; IL8 receptor; IL8 receptor type 1; IL8R1; IL8RA; IL8RBA; Interleukin 8 receptor alpha; Interleukin 8 receptor type 1; Interleukin 8 receptor type A;

抗原和靶标

免疫原:
Uniprot:

P25024(CXCR1_HUMAN) >>Visit HPA database.

基因/基因ID:
CXCR1(3577)
序列:
MSNITDPQMWDFDDLNFTGMPPADEDYSPCMLETETLNKYVVIIAYALVFLLSLLGNSLVMLVILYSRVGRSVTDVYLLNLALADLLFALTLPIWAASKVNGWIFGTFLCKVVSLLKEVNFYSGILLLACISVDRYLAIVHATRTLTQKRHLVKFVCLGCWGLSMNLSLPFFLFRQAYHPNNSSPVCYEVLGNDTAKWRMVLRILPHTFGFIVPLFVMLFCYGFTLRTLFKAHMGQKHRAMRVIFAVVLIFLLCWLPYNLVLLADTLMRTQVIQESCERRNNIGRALDATEILGFLHSCLNPIIYAFIGQNFRHGFLKILAMHGLVSKEFLARHRVTSYTSSSVNVSSNL

翻译修饰 - P25024 作为底物

Site PTM Type Enzyme
R279 Methylation
R280 Methylation

研究背景

功能:

Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity.

细胞定位:

Cell membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
蛋白家族:

Belongs to the G-protein coupled receptor 1 family.

研究领域

· Cellular Processes > Transport and catabolism > Endocytosis.   (View pathway)

· Environmental Information Processing > Signaling molecules and interaction > Cytokine-cytokine receptor interaction.   (View pathway)

· Environmental Information Processing > Signal transduction > Phospholipase D signaling pathway.   (View pathway)

· Human Diseases > Infectious diseases: Bacterial > Epithelial cell signaling in Helicobacter pylori infection.

· Organismal Systems > Immune system > Chemokine signaling pathway.   (View pathway)

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