AFfirm™ PPP1R14B Mouse Monoclonal Antibody - #BF9413

>>鼠单5折 进行中>>
产品: PPP1R14B 小鼠 单克隆 抗体
货号: BF9413
描述: Mouse monoclonal antibody to PPP1R14B
应用: WB
反应: Human
预测: Mouse, Rat, Pig, Horse, Rabbit, Dog
分子量: 16 kDa; 16kD(Calculated).
蛋白号: Q96C90

浏览相似产品>>

   规格 价格 库存
 100ul RMB¥ 1150 2300 现货

货期: 当天发货

联系销售
相关下载
MS Report
HPLC Report
MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Mouse
应用:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
克隆:
Monoclonal [AFfirm9413]
特异性:
PPP1R14B Mouse Monoclonal Antibody detects endogenous levels of total PPP1R14B.
偶联:
Unconjugated.
纯化:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

PHI 1; PHI1; Phospholipase C beta 3 neighboring gene protein; Phospholipase C beta 3 neighbouring gene protein; Phospholipase C-beta-3 neighbouring gene protein; PLCB3N; PNG; PP14B_HUMAN; Ppp1r14b; Protein phosphatase 1 regulatory (inhibitor) subunit 14B; Protein phosphatase 1 regulatory subunit 14B; SOM172;

抗原和靶标

免疫原:
Uniprot:

Q96C90(PP14B_HUMAN) >>Visit HPA database.

基因/基因ID:
PPP1R14B(26472)
表达:
Q96C90 PP14B_HUMAN:

Ubiquitous. Expressed at low levels.

序列:
MADSGTAGGAALAAPAPGPGSGGPGPRVYFQSPPGAAGEGPGGADDEGPVRRQGKVTVKYDRKELRKRLNLEEWILEQLTRLYDCQEEEIPELEIDVDELLDMESDDARAARVKELLVDCYKPTEAFISGLLDKIRGMQKLSTPQKK

翻译修饰 - Q96C90 作为底物

Site PTM Type Enzyme
A2 Acetylation
S4 Phosphorylation
S21 Phosphorylation
R27 Methylation
Y29 Phosphorylation
S32 Phosphorylation
T57 Phosphorylation O75116 (ROCK2) , P17252 (PRKCA) , Q05655 (PRKCD) , Q13418 (ILK)
K59 Acetylation
K59 Methylation
K114 Ubiquitination
Y121 Phosphorylation
K122 Ubiquitination
S142 Phosphorylation
T143 Phosphorylation

研究背景

功能:

Inhibitor of PPP1CA. Has over 50-fold higher inhibitory activity when phosphorylated (By similarity).

翻译修饰:

Phosphorylated primarily on Thr-57 by PKC (in vitro). An unknown Ser is also phosphorylated by PKC (in vitro) (By similarity).

细胞定位:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Ubiquitous. Expressed at low levels.

蛋白家族:

Belongs to the PP1 inhibitor family.

限制条款

产品的规格、报价、验证数据请以官网为准，官网链接：www.affbiotech.com | www.affbiotech.cn（简体中文）| www.affbiotech.jp（日本語）

产品的数据信息为Affinity所有，未经授权不得收集Affinity官网数据或资料用于商业用途，对抄袭产品数据的行为我们将保留诉诸法律的权利。

产品相关数据会因产品批次、产品检测情况随时调整，如您已订购该产品，请以订购时随货说明书为准，否则请以官网内容为准，官网内容有改动时恕不另行通知。

Affinity保证所销售产品均经过严格质量检测。如您购买的商品在规定时间内出现问题需要售后时，请您在Affinity官方渠道提交售后申请。

产品仅供科学研究使用。不用于诊断和治疗。 

产品未经授权不得转售。

Affinity Biosciences将不会对在使用我们的产品时可能发生的专利侵权或其他侵权行为负责。Affinity Biosciences, Affinity Biosciences标志和所有其他商标所有权归Affinity Biosciences LTD.