AFfirm™ FAKD5 Mouse Monoclonal Antibody - #BF9423

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产品: FAKD5 小鼠 单克隆 抗体
货号: BF9423
描述: Mouse monoclonal antibody to FAKD5
应用: WB
反应: Human
预测: Mouse, Horse, Rabbit, Dog
分子量: 87kDa; 87kD(Calculated).
蛋白号: Q7L8L6

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 100ul RMB¥ 1150 2300 现货

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产品描述

来源:
Mouse
应用:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
克隆:
Monoclonal [AFfirm9423]
特异性:
FAKD5 Mouse Monoclonal Antibody detects endogenous levels of total FAKD5.
偶联:
Unconjugated.
纯化:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

dJ1187M17.5; FAKD5_HUMAN; FAST kinase domain-containing protein 5; FAST kinase domains 5; FASTKD5; FLJ13149; FLJ58294;

抗原和靶标

免疫原:
Uniprot:

Q7L8L6(FAKD5_HUMAN) >>Visit HPA database.

基因/基因ID:
FASTKD5(60493)
表达:
Q7L8L6 FAKD5_HUMAN:

Expression detected in spleen, thymus, testis, ovary, colon, heart, smooth muscle, kidney, brain, lung, liver and white adipose tissue with highest expression in heart, smooth muscle, liver and thyroid.

序列:
MAATLKSLKLVRYRAFCSPSAFGAVRSVSYWNVSSTQHGGQDPPEHISLCHSAKKVKNICSTFSSRRILTTSSAHPGLEFSKTSSSKASTLQLGSPRATGVDEEDVEVFDSFENMRVFLQLRPEYRVHSYNASETSQLLSVSEGELILHKVRVNQNNLQAQVIVDYLCKLSSLPAEQHPVLLGSTSFALLCQLSVKKIQLFDTQDLINVLKAFVILGIPHSHSMLDVYETKCCHQVWEMNMDQLLLVADLWRYLGRKVPRFLNIFSSYLNLHWKDLSLSQLVHLIYVIGENRQVSQDLMQKLESLILKYIDLINLEEVGTICLGFFKSSTNLSEFVMRKIGDLACANIQHLSSRSLVNIVKMFRFTHVDHINFMKQIGEIAPQRIPSLGVQGVMHLTLYCSALRFLNEGVMNAVAASLPPRVAHCRSKDVAKILWSFGTLNYKPPNAEEFYSSLISEIHRKMPEFNQYPEHLPTCLLGLAFLEYFPVELIDFALSPGFVRLAQERTKFDLLKELYTLDGTVGIECPDYRGNRLSTHLQQEGSELLWYLAEKDMNSKPEFLETVFLLETMLGGPQYVKHHMILPHTRSSDLEVQLDVNLKPLPFNREATPAENVAKLRLEHVGVSLTDDLMNKLLKGKARGHFQGKTESEPGQQPMELENKAAVPLGGFLCNVADKSGAMEMAGLCPAACMQTPRMKLAVQFTNRNQYCYGSRDLLGLHNMKRRQLARLGYRVVELSYWEWLPLLKRTRLEKLAFLHEKVFTSAL

翻译修饰 - Q7L8L6 作为底物

Site PTM Type Enzyme
S7 Phosphorylation
S73 Phosphorylation
S81 Phosphorylation
K82 Ubiquitination
T83 Phosphorylation
K87 Ubiquitination
S95 Phosphorylation
T99 Phosphorylation
Y166 Phosphorylation
S171 Phosphorylation
K361 Ubiquitination
Y451 Phosphorylation
K507 Acetylation
T608 Phosphorylation
K615 Ubiquitination
C670 S-Nitrosylation
S676 Phosphorylation
T692 Phosphorylation
R704 Methylation
Y730 Phosphorylation
T761 Phosphorylation
S762 Phosphorylation

研究背景

功能:

Plays an important role in the processing of non-canonical mitochondrial mRNA precursors.

细胞定位:

Mitochondrion matrix>Mitochondrion nucleoid.
Note: Localizes to mitochondrial RNA granules found in close proximity to the mitochondrial nucleoids.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Expression detected in spleen, thymus, testis, ovary, colon, heart, smooth muscle, kidney, brain, lung, liver and white adipose tissue with highest expression in heart, smooth muscle, liver and thyroid.

亚基结构:

Found in a complex with GRSF1, DDX28, DHX30 and FASTKD2. Associates with the 12S mitochondrial rRNA (12S mt-rRNA).

蛋白家族:

Belongs to the FAST kinase family.

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