产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
展开/折叠
DNA directed DNA polymerase gamma; DNA polymerase subunit gamma 1; DNA polymerase subunit gamma-1; DPOG1_HUMAN; MDP 1; MDP1; Mitochondrial DNA polymerase catalytic subunit; Mitochondrial DNA polymerase gamma; PEO; POLG 1; POLG A; PolG alpha; POLG; PolG-alpha; POLG1; POLGA; Polymerase (DNA directed) gamma; SANDO; SCAE;
抗原和靶标
- P54098 DPOG1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSRLLWRKVAGATVGPGPVPAPGRWVSSSVPASDPSDGQRRRQQQQQQQQQQQQQPQQPQVLSSEGGQLRHNPLDIQMLSRGLHEQIFGQGGEMPGEAAVRRSVEHLQKHGLWGQPAVPLPDVELRLPPLYGDNLDQHFRLLAQKQSLPYLEAANLLLQAQLPPKPPAWAWAEGWTRYGPEGEAVPVAIPEERALVFDVEVCLAEGTCPTLAVAISPSAWYSWCSQRLVEERYSWTSQLSPADLIPLEVPTGASSPTQRDWQEQLVVGHNVSFDRAHIREQYLIQGSRMRFLDTMSMHMAISGLSSFQRSLWIAAKQGKHKVQPPTKQGQKSQRKARRGPAISSWDWLDISSVNSLAEVHRLYVGGPPLEKEPRELFVKGTMKDIRENFQDLMQYCAQDVWATHEVFQQQLPLFLERCPHPVTLAGMLEMGVSYLPVNQNWERYLAEAQGTYEELQREMKKSLMDLANDACQLLSGERYKEDPWLWDLEWDLQEFKQKKAKKVKKEPATASKLPIEGAGAPGDPMDQEDLGPCSEEEEFQQDVMARACLQKLKGTTELLPKRPQHLPGHPGWYRKLCPRLDDPAWTPGPSLLSLQMRVTPKLMALTWDGFPLHYSERHGWGYLVPGRRDNLAKLPTGTTLESAGVVCPYRAIESLYRKHCLEQGKQQLMPQEAGLAEEFLLTDNSAIWQTVEELDYLEVEAEAKMENLRAAVPGQPLALTARGGPKDTQPSYHHGNGPYNDVDIPGCWFFKLPHKDGNSCNVGSPFAKDFLPKMEDGTLQAGPGGASGPRALEINKMISFWRNAHKRISSQMVVWLPRSALPRAVIRHPDYDEEGLYGAILPQVVTAGTITRRAVEPTWLTASNARPDRVGSELKAMVQAPPGYTLVGADVDSQELWIAAVLGDAHFAGMHGCTAFGWMTLQGRKSRGTDLHSKTATTVGISREHAKIFNYGRIYGAGQPFAERLLMQFNHRLTQQEAAEKAQQMYAATKGLRWYRLSDEGEWLVRELNLPVDRTEGGWISLQDLRKVQRETARKSQWKKWEVVAERAWKGGTESEMFNKLESIATSDIPRTPVLGCCISRALEPSAVQEEFMTSRVNWVVQSSAVDYLHLMLVAMKWLFEEFAIDGRFCISIHDEVRYLVREEDRYRAALALQITNLLTRCMFAYKLGLNDLPQSVAFFSAVDIDRCLRKEVTMDCKTPSNPTGMERRYGIPQGEALDIYQIIELTKGSLEKRSQPGP
翻译修饰 - P54098 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K109 | Ubiquitination | Uniprot | |
| S296 | Phosphorylation | Uniprot | |
| K316 | Ubiquitination | Uniprot | |
| K321 | Ubiquitination | Uniprot | |
| K327 | Ubiquitination | Uniprot | |
| K371 | Ubiquitination | Uniprot | |
| K379 | Ubiquitination | Uniprot | |
| K383 | Ubiquitination | Uniprot | |
| S433 | Phosphorylation | Uniprot | |
| Y479 | Phosphorylation | Uniprot | |
| K551 | Ubiquitination | Uniprot | |
| K553 | Ubiquitination | Uniprot | |
| K561 | Ubiquitination | Uniprot | |
| K633 | Ubiquitination | Uniprot | |
| K658 | Ubiquitination | Uniprot | |
| K726 | Ubiquitination | Uniprot | |
| K755 | Ubiquitination | Uniprot | |
| K768 | Ubiquitination | Uniprot | |
| K773 | Ubiquitination | Uniprot | |
| K796 | Ubiquitination | Uniprot | |
| K934 | Ubiquitination | Uniprot | |
| K947 | Ubiquitination | Uniprot | |
| K981 | Ubiquitination | Uniprot | |
| K990 | Ubiquitination | Uniprot | |
| R1014 | Methylation | Uniprot | |
| K1040 | Ubiquitination | Uniprot | |
| K1050 | Ubiquitination | Uniprot | |
| K1060 | Ubiquitination | Uniprot | |
| K1191 | Ubiquitination | Uniprot | |
| K1198 | Ubiquitination | Uniprot | |
| Y1221 | Phosphorylation | Uniprot |
研究背景
Involved in the replication of mitochondrial DNA. Associates with mitochondrial DNA.
Mitochondrion. Mitochondrion matrix>Mitochondrion nucleoid.
Heterotrimer composed of a catalytic subunit and a homodimer of accessory subunits (By similarity). Interacts with TTC3.
Belongs to the DNA polymerase type-A family.
研究领域
· Metabolism > Global and overview maps > Metabolic pathways.
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