AFfirm™ ELAVL2 Mouse Monoclonal Antibody - #BF9452

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产品: ELAVL2 小鼠 单克隆 抗体
货号: BF9452
描述: Mouse monoclonal antibody to ELAVL2
应用: WB
反应: Human
预测: Mouse, Rat, Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
分子量: 38 KD; 40kD(Calculated).
蛋白号: Q12926

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   规格 价格 库存
 100ul RMB¥ 1150 2300 现货

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MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Mouse
应用:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
克隆:
Monoclonal [AFfirm9452]
特异性:
ELAVL2 Mouse Monoclonal Antibody detects endogenous levels of total ELAVL2.
偶联:
Unconjugated.
纯化:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

ELAV like neuron specific RNA binding protein 2; ELAV like Neuronal Protein 1; ELAV like Protein 2; ELAV-like neuronal protein 1; ELAV-like protein 2; ELAV2_HUMAN; ELAVL2; HEL-N1; HELN1; HU Antigen B; Hu-antigen B; HuB; Nervous System Specific RNA Binding Protein MelN1; Nervous system-specific RNA-binding protein Hel-N1;

抗原和靶标

免疫原:
Uniprot:

Q12926(ELAV2_HUMAN) >>Visit HPA database.

基因/基因ID:
ELAVL2(1993)
表达:
Q12926 ELAV2_HUMAN:

Brain; neural-specific.

序列:
METQLSNGPTCNNTANGPTTINNNCSSPVDSGNTEDSKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITVKFANNPSQKTNQAILSQLYQSPNRRYPGPLAQQAQRFRLDNLLNMAYGVKRFSPMTIDGMTSLAGINIPGHPGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKTHKA

翻译修饰 - Q12926 作为底物

Site PTM Type Enzyme
T51 Phosphorylation
K74 Ubiquitination
K95 Ubiquitination
T99 Phosphorylation
K111 Ubiquitination
Y114 Phosphorylation
S118 Phosphorylation
S119 Phosphorylation
T162 Phosphorylation
S165 Phosphorylation
K209 Ubiquitination
S221 Phosphorylation
K315 Ubiquitination

研究背景

功能:

RNA-binding protein that binds to the 3' untranslated region (3'UTR) of target mRNAs (By similarity). Seems to recognize a GAAA motif (By similarity). Can bind to its own 3'UTR, the FOS 3'UTR and the ID 3'UTR (By similarity).

组织特异性:

Brain; neural-specific.

亚基结构:

Interacts with IGF2BP1. Interacts with MAP1B light chain LC1 (By similarity).

蛋白家族:

Belongs to the RRM elav family.

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