AFfirm™ SDC2 Mouse Monoclonal Antibody - #BF9493

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产品: SDC2 小鼠单克隆 抗体
货号: BF9493
描述: Mouse monoclonal antibody to SDC2
应用: ELISA(peptide)
反应: Human
预测: Mouse, Rat, Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
分子量: 22kDa(Observed); 22kD(Calculated).
蛋白ID: P34741

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#BF9493-BP

SDC2 Peptide

1mg
相关下载
MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Mouse IgG
反应:
Human
克隆:
Monoclonal [AFfirm9493]
特异性:
SDC2 Mouse Monoclonal Antibody detects endogenous levels of total SDC2.
偶联:
Unconjugated.
纯化:
Affinity-chromatography.
保存:
Mouse IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

CD362; Fibroglycan; Heparan sulfate proteoglycan core protein; HSPG; SDC2; SDC2_HUMAN; SYND2; Syndecan-2;

抗原和靶标

免疫原:

A synthesized peptide derived from human SDC2, corresponding to a region within C-terminal amino acids.

Uniprot:

P34741(SDC2_HUMAN) >>Visit HPA database.

基因/基因ID:
SDC2(6383)
描述:
The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types. [provided by RefSeq, Jul 2008]
序列:
MRRAWILLTLGLVACVSAESRAELTSDKDMYLDNSSIEEASGVYPIDDDDYASASGSGADEDVESPELTTSRPLPKILLTSAAPKVETTTLNIQNKIPAQTKSPEETDKEKVHLSDSERKMDPAEEDTNVYTEKHSDSLFKRTEVLAAVIAGGVIGFLFAIFLILLLVYRMRKKDEGSYDLGERKPSSAAYQKAPTKEFYA

研究背景

功能:

Cell surface proteoglycan that bears heparan sulfate. Regulates dendritic arbor morphogenesis (By similarity).

翻译修饰:

O-glycosylated with core 1 or possibly core 8 glycans. Contains heparan sulfate.

细胞定位:

Membrane>Single-pass type I membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
蛋白家族:

Belongs to the syndecan proteoglycan family.

研究领域

· Environmental Information Processing > Signaling molecules and interaction > Cell adhesion molecules (CAMs).   (View pathway)

· Human Diseases > Infectious diseases: Parasitic > Malaria.

· Human Diseases > Cancers: Overview > Proteoglycans in cancer.

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