| 产品: | PPP1R9A 小鼠单克隆 抗体 |
| 货号: | BF9599 |
| 描述: | Mouse monoclonal antibody to PPP1R9A |
| 应用: | ELISA(peptide) |
| 反应: | Human, Mouse |
| 预测: | Pig, Horse, Sheep, Rabbit, Dog |
| 分子量: | 180 kDa(Observed); 123kD(Calculated). |
| 蛋白ID: | Q9ULJ8 |
产品描述
展开/折叠
FLJ20068; KIAA1222; NEB1_HUMAN; Neurabin I; Neurabin-1; Neurabin-I; Neurabin1; NeurabinI; Neural tissue specific F actin binding protein I; Neural tissue-specific F-actin-binding protein I; NRB 1; NRB I; NRB1; NRBI; Ppp1r9a; Protein phosphatase 1 regulatory (inhibitor) subunit 9A; Protein phosphatase 1 regulatory subunit 9A;
抗原和靶标
A synthesized peptide derived from human PPP1R9A, corresponding to a region within C-terminal amino acids.
- Q9ULJ8 NEB1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MLKTESSGERTTLRSASPHRNAYRTEFQALKSTFDKPKSDGEQKTKEGEGSQQSRGRKYGSNVNRIKNLFMQMGMEPNENAAVIAKTRGKGGHSSPQRRMKPKEFLEKTDGSVVKLESSVSERISRFDTMYDGPSYSKFTETRKMFERSVHESGQNNRYSPKKEKAGGSEPQDEWGGSKSNRGSTDSLDSLSSRTEAVSPTVSQLSAVFENTDSPSAIISEKAENNEYSVTGHYPLNLPSVTVTNLDTFGHLKDSNSWPPSNKRGVDTEDAHKSNATPVPEVASKSTSLASIPGEEIQQSKEPEDSTSNQQTPDSIDKDGPEEPCAESKAMPKSEIPSPQSQLLEDAEANLVGREAAKQQRKELAGGDFTSPDASASSCGKEVPEDSNNFDGSHVYMHSDYNVYRVRSRYNSDWGETGTEQDEEEDSDENSYYQPDMEYSEIVGLPEEEEIPANRKIKFSSAPIKVFNTYSNEDYDRRNDEVDPVAASAEYELEKRVEKLELFPVELEKDEDGLGISIIGMGVGADAGLEKLGIFVKTVTEGGAAQRDGRIQVNDQIVEVDGISLVGVTQNFAATVLRNTKGNVRFVIGREKPGQVSEVAQLISQTLEQERRQRELLEQHYAQYDADDDETGEYATDEEEDEVGPVLPGSDMAIEVFELPENEDMFSPSELDTSKLSHKFKELQIKHAVTEAEIQKLKTKLQAAENEKVRWELEKTQLQQNIEENKERMLKLESYWIEAQTLCHTVNEHLKETQSQYQALEKKYNKAKKLIKDFQQKELDFIKRQEAERKKIEDLEKAHLVEVQGLQVRIRDLEAEVFRLLKQNGTQVNNNNNIFERRTSLGEVSKGDTMENLDGKQTSCQDGLSQDLNEAVPETERLDSKALKTRAQLSVKNRRQRPSRTRLYDSVSSTDGEDSLERKNFTFNDDFSPSSTSSADLSGLGAEPKTPGLSQSLALSSDESLDMIDDEILDDGQSPKHSQCQNRAVQEWSVQQVSHWLMSLNLEQYVSEFSAQNITGEQLLQLDGNKLKALGMTASQDRAVVKKKLKEMKMSLEKARKAQEKMEKQREKLRRKEQEQMQRKSKKTEKMTSTTAEGAGEQ
研究背景
Binds to actin filaments (F-actin) and shows cross-linking activity. Binds along the sides of the F-actin. May be involved in neurite formation. Inhibits protein phosphatase 1-alpha activity (By similarity).
Cytoplasm>Cytoskeleton. Cell junction>Synapse>Synaptosome.
Interacts with p70-S6K via its PDZ domain.
The PP1 binding region is natively unstructured, upon PP1 binding, it acquires structure, blocks a substrate-binding site, and restricts PP1 phosphatase specificity to a subset of substrates.
限制条款
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