Tegoprubart - #BF6321
产品描述
货号:
BF6321
简介:
Tegoprubart (AT-1501) is a CD40 ligand inhibitor (EC50=100 ng/mL) and immunosuppressant that selectively inhibits the CD40 ligand, a co-stimulatory molecule involved in T cell activation. Tegoprubart suppresses immune rejection, prevents rejection in animal transplantation models, and reduces cell-mediated and antibody-mediated immune responses to create a more immunotolerant environment. Tegoprubart exhibits acceptable safety and tolerability in kidney transplant recipients, preserves renal function when combined with Mycophenolate and Corticosteroids, and maintains graft function in preclinical studies. Tegoprubart is applicable to research related to kidney transplantation and kidney transplant rejection.
别名:
AT-1501
靶标:
CD40L
蛋白ID:
P29965
基因ID:
959
分子量:
145.56 kDa
应用:
FACS, ELISA, Functional assay
反应:
Human
CAS NO.:
2628092-47-5
运输方式:
Shipping with dry ice.
缓冲液:
Supplied as a 0.22 μm filtered solution in PBS, pH 7.2
储存条件:
Store at -80°C for 2 years. Aliquots should be stored at the same temperature after first use to avoid
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